Results 91 to 100 of about 3,785 (176)
Genome‐wide copy‐number variation landscape highlights structural divergence across Puccinia hordei isolates and potentially links Cyp51 amplification to fungicide insensitivity. Summary Leaf rust, caused by Puccinia hordei, is a major barley disease worldwide.
Xiaohui Yu +6 more
wiley +1 more source
SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu +5 more
wiley +1 more source
Mer ansvar - mer frigjøring? [PDF]
openaire +1 more source
Molecular dynamics simulations of oleuropein diffusion in chitosan‐based nanoparticles
Abstract BACKGROUND This study explores the diffusion mechanisms of oleuropein (OLE), a promising polyphenolic compound, within chitosan‐based nanoparticles using molecular dynamics simulations. Chitosan nanoparticles serve as drug delivery carriers, leveraging biocompatibility and tunable release properties influenced by environmental factors such as ...
Bernardino Tirri +3 more
wiley +1 more source
Abstract In numerous neurodegenerative diseases known collectively as tauopathies, the microtubule‐associated protein tau forms fibrillar aggregates that are hallmarks of disease pathology. Tauopathies represent a substantial fraction of diseases associated with protein misfolding.
Mia Cervantes +5 more
wiley +1 more source
Benchmarking of Reference‐Based Tools for Strain‐Level Resolution of Plant Microbiome
ABSTRACT Strain‐level identification of each microbe is crucial for understanding its role in the host. Most of the existing tools have primarily been evaluated on human metagenomic datasets, whereas the plant microbiome exhibits greater diversity and complexity and thus poses a challenge in the strain‐level resolution of individual microbes.
Rishav Sahil, Mukesh Jain
wiley +1 more source
Expression of Active Apurinic Apyrimidinic Endodeoxyribonuclease 1 in Human Platelets
Platelets (PLTs) isolated from healthy donors contain variable amounts of enzymatically active APE1, likely surveilling mitochondrial DNA integrity and overall mitochondria functioning. The use of the specific APE1 inhibitor compound #3 on platelet rich plasma (PRP) significantly impairs the PLTs' aggregation properties of activated PLTs triggered only
Isabella Parolini +9 more
wiley +1 more source
Interaction‐Driven Assembly Pathways in Heterogeneous Active Microrobotic Systems
Peanut‐ and cube‐shaped light‐powered microrobots exhibit distinct magnetic and photocatalytic responses that determine their heterogeneous self‐assembly. In the dark, magnetic dipole interactions drive colloidal copolymerization with cubes acting as nucleation centers, whereas under light irradiation, phoretic interactions compete with magnetic ...
Domenico Calabrò +5 more
wiley +1 more source
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding +13 more
wiley +1 more source

