Results 91 to 100 of about 102,530 (235)
Meningitis-Retention Syndrome with mild encephalitis/ encephalopathy with reversible splenial lesion
Meningitis-retention syndrome is a rare condition characterized by meningitis with urinary retention. We report a case of recurrent meningitis-retention syndrome as a symptom of mild encephalitis/encephalopathy with reversible splenial lesion in a 42 ...
Naoko Makishi, Yasuharu Tokuda
doaj +1 more source
Repurposed Medicines for Viruses With Epidemic or Pandemic Potential: A Horizon Scan. [PDF]
ABSTRACT Viruses such as Ebola, Marburg, influenza, mpox, MERS‐CoV, SARS‐CoV, and SARS‐CoV‐2 may be considered pathogens of epidemic or pandemic concern. Developing novel antiviral medicines can be time‐consuming and resource intensive. Repurposing existing medicines with known or potential antiviral activity offers a faster, cost‐effective strategy to
Akinbolade S +5 more
europepmc +2 more sources
Under physiological conditions, pathogenic stimuli activate TLR/IL1‐R signaling, triggering TOLLIP dissociation from IRAK1 and subsequent IRAK1 phosphorylation, TRAF6 ubiquitination, and NF‐κB activation. During SARS‐CoV‐2 infection, viral M protein binds TOLLIP and stabilizes the TOLLIP–IRAK1 complex, thereby suppressing NF‐κB signaling, impairing ...
Yabin Zhang +10 more
wiley +1 more source
The introduction of a single hydrophobic residue at the C‐terminus of short cationic peptides enhances passive translocation and cellular uptake. ABSTRACT Cationic cell‐penetrating peptides (CPPs) are a versatile platform for intracellular cargo delivery into mammalian cells but often suffer from low cellular uptake and endosomal entrapment.
Adeline Schmitt, Helma Wennemers
wiley +1 more source
ABSTRACT Rainbow trout (Oncorhynchus mykiss) exhibit extensive genomic diversity shaped by domestication, life history and geographic origin. To advance the development of a comprehensive pangenome reference, we present new de novo genome assemblies of two genetically and ecologically distinct lines: Whale Rock (WR; wild, landlocked, Central California)
Ali Ali +9 more
wiley +1 more source
Citation: 'mer-' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03828 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms. Requests for commercial usage of
openaire +1 more source
Changes over time in hallucinogen‐related emergency department visits in Ontario, Canada
Abstract Background and aims Recent increasing interest in hallucinogens has underscored the critical gaps in our understanding of their adverse health effects and healthcare usage over time. The current study aimed to examine changes in emergency department (ED) visit rates involving hallucinogens, clinical outcomes of visits and the characteristics ...
Daniel T. Myran +9 more
wiley +1 more source
Abstract This study investigates the claim that women are disproportionately more likely to die in disasters by reviewing existing data sources and compiling new datasets on sex‐differentiated disaster fatalities in the twenty‐first century. The analysis is structured by disaster type, covering geophysical, meteorological, climatological, hydrological,
Olivier Rubin
wiley +1 more source
LLM‐Assisted Topic Modelling for Hate Speech Characterization
ABSTRACT In the digital era, the internet and social media have transformed communication but have also facilitated the spread of hate speech and disinformation, leading to radicalization, polarisation and toxicity. This is especially concerning for media outlets due to their significant role in shaping public discourse. This study examines the topics,
Alejandro Buitrago López +2 more
wiley +1 more source
Summary High‐throughput molecular studies of museum specimens (museomics) have great potential in biodiversity research, but fungal historical collections have scarcely been examined, leading to no comprehensive methodological assessments. Here we present a whole genome sequencing (WGS) project conducted at the Fungarium of the Royal Botanic Gardens ...
Torda Varga +24 more
wiley +1 more source

