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Coronaviruses: SARS, MERS and COVID-19
Coronaviruses were originally discovered as enzootic infections that limited to their natural animal hosts, but some strains have since crossed the animal-human species barrier and progressed to establish zoonotic diseases.
Eun-Joong Kim, Dongsup Lee
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Digesting the crisis: autophagy and coronaviruses
Autophagy is a catabolic pathway with multifaceted roles in cellular homeostasis. This process is also involved in the antiviral response at multiple levels, including the direct elimination of intruding viruses (virophagy), the presentation of viral ...
Didac Carmona-Gutierrez +6 more
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COVID-19: benefits and risks of passive immunotherapeutics
Passive immunotherapeutics (PITs), including convalescent plasma, serum, or hyperimmune immunoglobulin, have been of clinical importance during sudden outbreaks since the early twentieth century for the treatment of viral diseases such as severe acute ...
Ankur Gupta +5 more
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Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirus [PDF]
The Middle East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Arabia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% mortality.
Al Rabeeah, Abdullah A. +20 more
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COMPARISON between COVID-19 and MERS demographic data in Saudi Arabia: a retrospective study
The outbreak of corona virus disease (COVID-19) caused by the new severe acute respiratory syndrome corona virus 2 began in Wuhan, China, resulting in respiratory disorders.
Rania Ali El Hadi Mohamed +1 more
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Coronavirus disease – 2019 (COVID-19) pandemic, due to severe acute respiratory syndrome– coronavirus-2 (SARS-CoV-2), is posing a severe bio threat to the entire world.
Shantani Kannan +3 more
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Role of cytokine storm in coronavirus infections: culprit or accomplice?
At present, there are seven known types of human coronaviruses (HCoVs), which can be further divided into two categories: low pathogenic and highly pathogenic.
Rongpeng Xu +5 more
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Prediction of Intrinsic Disorder in MERS-CoV/HCoV-EMC Supports a High Oral-Fecal Transmission [PDF]
A novel coronavirus, MERS-CoV (NCoV, HCoV-EMC/2012), originating from the Middle-East, has been discovered. Incoming data reveal that the virus is highly virulent to humans.
Dunker, A. Keith +2 more
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Middle East respiratory syndrome coronavirus in the last two years: Health care workers still at risk [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
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Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2
SARS-CoV-2, the virus causing COVID-19, is a single-stranded RNA virus belonging to the order Nidovirales, family Coronaviridae, and subfamily Coronavirinae.
Mohamad Hesam Shahrajabian +2 more
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