Results 31 to 40 of about 102,530 (235)
Digesting the crisis: autophagy and coronaviruses
Microbial Cell, 2020 Autophagy is a catabolic pathway with multifaceted roles in cellular homeostasis. This process is also involved in the antiviral response at multiple levels, including the direct elimination of intruding viruses (virophagy), the presentation of viral ...
Didac Carmona-Gutierrez +6 more
doaj +1 more source
Coronaviruses: SARS, MERS and COVID-19
Korean Journal of Clinical Laboratory Science, 2020 Coronaviruses were originally discovered as enzootic infections that limited to their natural animal hosts, but some strains have since crossed the animal-human species barrier and progressed to establish zoonotic diseases.
Eun-Joong Kim, Dongsup Lee
doaj +1 more source
COVID-19: benefits and risks of passive immunotherapeutics
Human Vaccines & Immunotherapeutics, 2020 Passive immunotherapeutics (PITs), including convalescent plasma, serum, or hyperimmune immunoglobulin, have been of clinical importance during sudden outbreaks since the early twentieth century for the treatment of viral diseases such as severe acute ...
Ankur Gupta +5 more
doaj +1 more source
COMPARISON between COVID-19 and MERS demographic data in Saudi Arabia: a retrospective study
Libyan Journal of Medicine, 2021 The outbreak of corona virus disease (COVID-19) caused by the new severe acute respiratory syndrome corona virus 2 began in Wuhan, China, resulting in respiratory disorders.
Rania Ali El Hadi Mohamed +1 more
doaj +1 more source
Motor Evoked Potentials Improve Targeting in Deep Brain Stimulation Surgery
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Objectives One of the main challenges posed by the surgical deep brain stimulation (DBS) procedure is the successful targeting of the structures of interest and avoidance of side effects, especially in asleep surgery. Here, intraoperative motor evoked potentials (MEPs) might serve as tool to identify the pyramidal tract.
Petyo Nikolov +7 more
wiley +1 more source
Journal of Pure and Applied Microbiology, 2020 Coronavirus disease – 2019 (COVID-19) pandemic, due to severe acute respiratory syndrome– coronavirus-2 (SARS-CoV-2), is posing a severe bio threat to the entire world.
Shantani Kannan +3 more
doaj +1 more source
Role of cytokine storm in coronavirus infections: culprit or accomplice?
Frontiers in Bioscience-Landmark, 2022 At present, there are seven known types of human coronaviruses (HCoVs), which can be further divided into two categories: low pathogenic and highly pathogenic.
Rongpeng Xu +5 more
doaj +1 more source
Angewandte Chemie, EarlyView.The impact of C‐3 fluorination on the synthesis and conformation of alginate oligosaccharides is investigated. A C‐3‐fluoro mannuronic acid building block is generated and shown to react with high β‐selectivity. Automated glycan assembly enables access to uniquely fluorinated mannuronic acid alginates where deoxyfluorination is shown not to perturb the
Sean T. Evans +10 more
wiley +2 more sources
Product of natural evolution (SARS, MERS, and SARS-CoV-2); deadly diseases, from SARS to SARS-CoV-2
Human Vaccines & Immunotherapeutics, 2021 SARS-CoV-2, the virus causing COVID-19, is a single-stranded RNA virus belonging to the order Nidovirales, family Coronaviridae, and subfamily Coronavirinae.
Mohamad Hesam Shahrajabian +2 more
doaj +1 more source
Targeting Middle East Respiratory Syndrome Coronavirus Spike Fusion Machinery With Antiviral Peptides: In Silico Exploration of the Heptad Repeat 2 Domain. [PDF]
MicrobiologyopenGriffithsin, Brevinin‐2, and CCL20 were identified as potent MERS‐CoV fusion inhibitor candidates targeting the HR2 domain through integrated molecular docking, MD simulations, and MM/PBSA analyses. These peptides demonstrated superior binding stability and favorable safety profiles compared to the standard inhibitor, supporting their potential as ...
Alotaiq N, Dermawan D, Chtita S.
europepmc +2 more sources