Results 41 to 50 of about 102,530 (235)

Diagnostic and therapeutic difficulty of chondrosarcoma of the temporomandibular joint: Two cases report

open access: yesOral and Maxillofacial Surgery Cases, 2021
Chondrosarcoma is a malignant tumor characterized by cartilaginous formation. It represents approximately 0.1% of all head and neck neoplasms. Its localization in the temporomandibular joint (TMJ) remains extremely rare.
Salissou Iro, Faiçal Slimani
doaj   +1 more source

Mer [PDF]

open access: yesAnthropen, 2018
Comment la mer pourrait-elle constituer un "objet" anthropologique? Quelles différences de traitements et d'analyses a-t-elle stimulée? Et pourquoi est-elle passée en quelques décennies de la périphérie vers le cœur des sciences humaines?
openaire   +1 more source

Analyzing the MERS disease control strategy through an optimal control problem

open access: yesInternational Journal of Applied Mathematics and Computer Science, 2018
A deterministic mathematical model of the Middle East respiratory syndrome (MERS) disease is introduced. Medical masks, supportive care treatment and a government campaign about the importance of medical masks will be involved in the model as time ...
Aldila Dipo   +4 more
doaj   +1 more source

Hijacking the Host Clock: A Nematode Effector Antagonizes Soybean Circadian Defense and Translation Control

open access: yesAdvanced Science, EarlyView.
Soybean employs its circadian clock, governed by GmCCA1, to rhythmically defend against soybean cyst nematodes. The pathogen retaliates by secreting the effector Hg4E02, which hijacks the clock to suppress defense and co‐opt the host's translation machinery for nutrient acquisition.
Xingwei Wang   +21 more
wiley   +1 more source

Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels

open access: yesVaccines, 2022
The Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic pathogen that can transmit from dromedary camels to humans, causing severe pneumonia, with a 35% mortality rate.
Naif Khalaf Alharbi   +11 more
doaj   +1 more source

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

open access: yesAdvanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti   +13 more
wiley   +1 more source

RNA‐Binding Protein RBM25 Targets the mRNA Stability of GTPase Rab22a to Restrict Viral Entry and Infection

open access: yesAdvanced Science, EarlyView.
This study identifies RNA‐binding protein RBM25 as a broad‐spectrum antiviral factor acting independently of type I interferon. It blocks viral entry by suppressing GTPase Rab22a via the RC3H1‐mediated destabilization of Rab22a mRNA. Viral downregulation of RBM25 enhances GTPase Rab22a expression and viral entry, revealing an unreported post ...
Yingying Ding   +13 more
wiley   +1 more source

Vaccines for epidemic infections and the role of CEPI

open access: yesHuman Vaccines & Immunotherapeutics, 2017
The author reviews the foundation of the Coalition for Epidemic Preparedness and Innovations and the choices it has made for funding of vaccine development against epidemic diseases.
Stanley A. Plotkin
doaj   +1 more source

Epidemics and Reforms: Experience of Saudi Arabia

open access: yesМеждународная аналитика, 2020
Saudi Arabia is one of the key countries in the Middle East and the Arab-Muslim world. The processes developing in this country, determined by both internal and external factors, are directly related to the development of the surrounding geopolitical ...
G. G. Kosach
doaj   +1 more source

When Biology Meets Medicine: A Perspective on Foundation Models

open access: yesAdvanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu   +3 more
wiley   +1 more source

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