Results 61 to 70 of about 340,715 (262)

When Biology Meets Medicine: A Perspective on Foundation Models

Advanced Intelligent Discovery, EarlyView.
Artificial intelligence, and foundation models in particular, are transforming life sciences and medicine. This perspective reviews biological and medical foundation models across scales, highlighting key challenges in data availability, model evaluation, and architectural design.
Kunying Niu, Yuxing Wang, Limin Zou, Jing Huang   +3 more
wiley   +1 more source

Percolation of linear $k$-mers on square lattice: from isotropic through partially ordered to completely aligned state

, 2012
Numerical simulations by means of Monte Carlo method and finite-size scaling analysis have been performed to study the percolation behavior of linear $k$-mers (also denoted in the literature as rigid rods, needles, sticks) on two-dimensional square ...
Laptev, Valeri V., Lebovka, Nikolai I., Tarasevich, Yuri Yu.   +2 more
core   +1 more source

The effect of the lateral interactions on the critical behavior of long straight rigid rods on two-dimensional lattices [PDF]

, 2009
Using Monte Carlo simulations and finite-size scaling analysis, the critical behavior of attractive rigid rods of length k (k-mers) on square lattices at intermediate density has been studied.
Linares, D. H., Longone, P., Ramirez-Pastor, A. J.   +2 more
core   +3 more sources

Zebrafish and CRISPR—A synergistic approach to decipher and cure human diseases

Animal Models and Experimental Medicine, EarlyView.
Zebrafish, with high genetic homology to humans, serves as a powerful vertebrate model for disease modeling and drug discovery. Integration of CRISPR/Cas9 technology enables precise genome editing, facilitating the development of translational models for human diseases.
Manikandan Sivaprakasam, Aashika Raagavi Jeanpierre, Salma Mohammed, Rajesh Srinivasan, Aman Kumar Mohanty   +4 more
wiley   +1 more source

Update on therapeutic options for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) [PDF]

, 2016
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Memish, Ziad A.
core   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

These are not the k-mers you are looking for: efficient online k-mer counting using a probabilistic data structure

, 2014
K-mer abundance analysis is widely used for many purposes in nucleotide sequence analysis, including data preprocessing for de novo assembly, repeat detection, and sequencing coverage estimation.
Brown, C. Titus, Canino-Koning, Rosangela, Howe, Adina Chuang, Pell, Jason, Zhang, Qingpeng   +4 more
core   +2 more sources

Emerging viral respiratory tract infections—environmental risk factors and transmission [PDF]

, 2014
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Al-Tawfiq, Jaffar A., Charrel, Remi N., Gautret, Philippe, Gray, Gregory C., Memish, Ziad A., Odezulu, Nnanyelugo G., Zumla, Alimuddin   +6 more
core   +1 more source

L'origine des noms de mer Rouge, mer Blanche et mer Noire

Le Globe. Revue genevoise de géographie, 1924
de Saussure Léopold. L'origine des noms de mer Rouge, mer Blanche et mer Noire. In: Le Globe. Revue genevoise de géographie, tome 63, 1924. pp. 23-36.
openaire   +3 more sources

RBD‐SD1 Nanoparticle Vaccines From DPP4‐Using Merbecoviruses Elicit a Cross‐Reactive Antibody Response but Limited Cross‐Protective Immunity

Biotechnology and Bioengineering, EarlyView.
SpyCatcher‐mi3 nanoparticles displaying RBD‐SD1 from MERS‐CoV, NL140422, and HKU4 elicited robust and cross‐reactive IgG responses in mice. Only MERS‐CoV RBD‐SD1 induced neutralizing antibodies against MERS‐CoV and protected human DPP4 mice from a MERS‐CoV challenge, indicating conserved serologic but limited cross‐neutralizing epitopes.
Peter J. Halfmann, Jeong Soo Lee, Tong Wang, Augustine Duffy, Janie E. Rogers, Natasha Chen, Elizabeth Frimpong, Carmen Rai, Yoshihiro Kawaoka, Ravi S. Kane   +9 more
wiley   +1 more source