Results 51 to 60 of about 340,715 (262)
Immunogenicity of High-Dose MVA-Based MERS Vaccine Candidate in Mice and Camels
Vaccines, 2022 The Middle East respiratory syndrome coronavirus (MERS-CoV) is a zoonotic pathogen that can transmit from dromedary camels to humans, causing severe pneumonia, with a 35% mortality rate.
Naif Khalaf Alharbi +11 more
doaj +1 more source
Spaced seeds improve k-mer-based metagenomic classification [PDF]
, 2015 Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel +2 more
core +2 more sources
Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses
Advanced Science, EarlyView.ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti +13 more
wiley +1 more source
Gerbil: A Fast and Memory-Efficient $k$-mer Counter with GPU-Support [PDF]
, 2016 A basic task in bioinformatics is the counting of $k$-mers in genome strings. The $k$-mer counting problem is to build a histogram of all substrings of length $k$ in a given genome sequence.
Erbert, Marius +2 more
core +2 more sources
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source
Vaccines for epidemic infections and the role of CEPI
Human Vaccines & Immunotherapeutics, 2017 The author reviews the foundation of the Coalition for Epidemic Preparedness and Innovations and the choices it has made for funding of vaccine development against epidemic diseases.
Stanley A. Plotkin
doaj +1 more source
Response to the letter to the editor regarding “safety of tenecteplase versus alteplase for intravenous thrombolysis in acute ischemic stroke patients with direct oral anticoagulation” [PDF]
Neurological Research and PracticeLena Mers, Stefan T. Gerner
doaj +2 more sources
Advanced Science, EarlyView.This review outlines bottom‐up and biomimetic fabrication strategies of quantum dots, and highlights their emerging applications in biosensing, multimodal bioimaging, and intelligent cancer theranostics. It further discusses key translational barriers and future perspectives for advancing QD‐based nanomedicine toward clinical implementation.
Jie Ju +5 more
wiley +1 more source
Prospects for a MERS-CoV spike vaccine
Expert Review of Vaccines, 2018 Introduction: Six years have passed since Middle East respiratory syndrome (MERS) coronavirus (MERS-CoV), a newly emerging infectious virus, was first reported in 2012.
Yusen Zhou, Shibo Jiang, Lanying Du
doaj +1 more source
Epidemics and Reforms: Experience of Saudi Arabia
Международная аналитика, 2020 Saudi Arabia is one of the key countries in the Middle East and the Arab-Muslim world. The processes developing in this country, determined by both internal and external factors, are directly related to the development of the surrounding geopolitical ...
G. G. Kosach
doaj +1 more source