Results 81 to 90 of about 10,738 (252)

The Role of Mesalamine in the Treatment of Ulcerative Colitis [PDF]

open access: yes, 2013
Ulcerative colitis (UC) is a chronic inflammatory condition of unclear etiology affecting the large bowel, most commonly the rectum and extending proximally in a continuous fashion. The overall principle in the pathophysiolgy of ulcerative colitis is the
Burakoff, Robert, Karagozian, Raffi
core  

Drug‐Induced Renal Vasculitis: Etiology, Pathogenesis, Clinical Manifestations, and Therapeutic Approaches—A Narrative Review

open access: yesHealth Science Reports, Volume 8, Issue 4, April 2025.
ABSTRACT Background and Aims Drug‐induced renal vasculitis arises from various medications that cause immunological dysregulation or direct vascular damage, leading to inflammation and thrombosis. Clinical manifestations vary widely, from mild constitutional symptoms to severe organ dysfunction. This review aims to thoroughly explore drug‐induced renal
Hashim Mohamed Siraj   +7 more
wiley   +1 more source

A novel pH–enzyme-dependent mesalamine colon-specific delivery system

open access: yesDrug Design, Development and Therapy, 2016
Lei Jin, Yi-cun Ding, Yu Zhang, Xiao-qing Xu, Qin Cao Department of Gastroenterology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai, People’s Republic of China Abstract: The aim of the present study was to ...
Jin L, Ding Y, Zhang Y, Xu X, Cao Q
doaj  

Pathophysiology of IBD as a Key Strategy for Polymeric Nanoparticle Development

open access: yesAdvanced Therapeutics, Volume 8, Issue 3, March 2025.
Polymeric nanoparticles are a promising approach for targeted drug delivery in case of patients with inflammatory bowel disease (IBD). IBD is a complex chronic gastrointestinal disease with compromised gastrointestinal barrier integrity, mucosal barrier alterations, altered cell surface receptor patterns, and oxidative stress. This review discusses how
Elena Gardey   +2 more
wiley   +1 more source

Updating predictors of endoscopic recurrence after ileocolic resection for Crohn disease [PDF]

open access: yes, 2017
Background/Aims: Identifying predictors of endoscopic recurrence (ER) has become very important to guide the decision of postoperative strategy. This study aimed to determine the rate of endoscopic recurrence until 12 months after ileocolic resection for
Carvalho, Pedro Boal   +4 more
core   +1 more source

Approach to anaemia in gastrointestinal disease: A position paper by the ESPGHAN Gastroenterology Committee

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 80, Issue 3, Page 510-532, March 2025.
Approach to Anaemia in paediatric Gastrointestinal Disease Abstract Anaemia is a frequent consequence of many gastrointestinal (GI) diseases in children and it can even be the initial presenting symptom of underlying chronic GI disease. The definition of anaemia is age and gender‐dependent and it can be classified based on pathophysiology, red cell ...
Ilse Julia Broekaert   +12 more
wiley   +1 more source

Maintaining remission in ulcerative colitis – role of once daily extended-release mesalamine

open access: yesDrug Design, Development and Therapy, 2011
Lilliana Oliveira, Russell D CohenThe Department of Medicine, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USAAbstract: The aminosalicylates (5-ASA; also referred to as mesalamine-based agents) are considered as first ...
Lilliana Oliveira, Russell D Cohen
doaj  

Nephrotic syndrome after treatment of Crohn′s disease with mesalamine: Case report and literature review

open access: yesAvicenna Journal of Medicine, 2012
Inflammatory bowel disease and its various treatments may affect the kidney in several ways. Recently, case reports have been published documenting the development of nephrotic syndrome after the treatment for inflammatory bowel disease with 5 ...
Belal M Firwana   +6 more
doaj   +1 more source

Optimizing the Use of Current Treatments and Emerging Therapeutic Approaches to Achieve Therapeutic Success in Patients with Inflammatory Bowel Disease

open access: yesGut and Liver, 2020
The current goal of inflammatory bowel disease (IBD) treatment is a symptom-free everyday life accompanied by mucosal healing with minimal use of corticosteroids.
Hiroshi Nakase
doaj   +1 more source

Simple one-pot green method for large-scale production of mesalamine, an anti-inflammatory agent

open access: yesGreen Processing and Synthesis, 2019
We report a rapid and efficient synthesis protocol for mesalamine via a green approach with 2-chloro-5-nitrobenzoic acid as the starting material, for its large-scale production.
Vijaya Lakshmi C.   +2 more
doaj   +1 more source

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