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Statement of Retraction: β-Patchoulene represses hypoxia-induced proliferation and epithelial-mesenchymal transition of liver cancer cells. [PDF]

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Mesenchymal-to-epithelial transition of osteoblasts induced by Fam20c knockout

Genes & Genomics, 2022
Fam20c is intimately related to tissue development and diseases. At present, it has been reported that Fam20c regulates the mineralization of osteoblasts, but there are few reports on other effects.To study the effect of Fam20c on osteoblasts by knocking out the Fam20c gene.Fam20c knockout osteoblasts were constructed by transfecting mouse osteoblasts ...
Ya-Wei Geng, Zhen Zhang, Han Jin, Jun-Long Da, Kai Zhang, Jian-Qun Wang, Yu-Yao Guo, Bin Zhang, Ying Li   +8 more
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Mesenchymal to epithelial transition in sarcomas

European Journal of Cancer, 2014
Mesenchymal to epithelial transition (MET) in carcinomas has been proposed to promote the growth of epithelial tumour cells at distant sites during metastasis. MET has also been suggested as an important biological and clinical process in mesenchymal tumors, sarcomas.
Jilong Yang, Xiaoling Du, Guowen Wang, Yan Sun, Kexin Chen, Xiongzeng Zhu, Alexander J.F. Lazar, Kelly K. Hunt, Raphael E. Pollock, Wei Zhang   +9 more
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Mesenchymal-to-Epithelial Transitions in Development and Cancer

2020
The evolutionary emergence of the mesenchymal phenotype greatly increased the complexity of tissue architecture and composition in early Metazoan species. At the molecular level, an epithelial-to-mesenchymal transition (EMT) was permitted by the innovation of specific transcription factors whose expression is sufficient to repress the epithelial ...
John-Poul, Ng-Blichfeldt, Katja, Röper
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Mesenchymal to Epithelial Transition in Development and Disease

Cells Tissues Organs, 2007
Cellular plasticity is fundamental to embryonic development. The importance of cellular transitions in development is first apparent during gastrulation when the process of epithelial to mesenchymal transition transforms polarized epithelial cells into migratory mesenchymal cells that constitute the embryonic and extraembryonic mesoderm.
Chaffer, Christine, Thompson, Rik, Williams, Elizabeth   +2 more
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The mesenchymal-to-epithelial transition in somatic cell reprogramming

Current Opinion in Genetics & Development, 2012
The epithelial-to-mesenchymal transition (EMT) is a process that confers migratory characteristics to epithelial cells. It is a major force driving embryonic development, tissue fibrosis and malignant progression, and can also create cells with properties of stem cells.
Miguel A, Esteban, Xichen, Bao, Qiang, Zhuang, Ting, Zhou, Baoming, Qin, Duanqing, Pei   +5 more
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Mesenchymal-to-epithelial transition in the placental tissues of patients with preeclampsia

Hypertension Research, 2016
During early pregnancy in humans, mesenchymal-to-epithelial transition (MET) contributes to decidualization of endometrial stromal cells in the uterus. Defects in decidualization can interfere with placental formation and can lead to pregnancy complications, including preeclampsia.
Lili, Du, Liyun, Kuang, Fang, He, Wenting, Tang, Wen, Sun, Dunjin, Chen   +5 more
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Hyaluronan: A Critical Component of Epithelial-Mesenchymal and Epithelial-Carcinoma Transitions

Cells Tissues Organs, 2005
Hyaluronan plays a central role in the transition of epithelia to mesenchyme in the embryo and in the acquisition of transformed properties in carcinoma cells. In some cases, hyaluronan is both essential and sufficient for induction of epithelial-mesenchymal transitions (EMTs).
Bryan P, Toole, Alexandra, Zoltan-Jones, Suniti, Misra, Shibnath, Ghatak   +3 more
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Genes and proteins involved in mesenchymal to epithelial transition

Current Opinion in Nephrology and Hypertension, 2001
It has been known for many years that the epithelia of the urogenital system derive from mesenchyme. Essential regulators of this conversion have recently been discovered, and cellular changes have been described. However, we do not have a coherent view of how these dramatic changes are integrated, nor do we know the source or identity of extracellular
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Mesenchymal-to-epithelial transition determinants as characteristics of ovarian carcinoma effusions

Clinical & Experimental Metastasis, 2010
The present study investigated the intracellular regulation of E-cadherin in ovarian carcinoma. E-cadherin expression and regulation by Snail and Pak1 were studied in ES-2 and OVCAR-3 ovarian cancer cells in vitro. Twist1, Zeb1 and Vimentin mRNA expression and HIF-1alpha protein expression were analyzed in 80 and 189 clinical specimens, respectively ...
Sivan, Elloul, Olga, Vaksman, Helene Tuft, Stavnes, Claes G, Trope, Ben, Davidson, Reuven, Reich   +5 more
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