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The function and regulation of mesenchymal-to-epithelial transition in somatic cell reprogramming

Current Opinion in Genetics & Development, 2014
The process that converts somatic cells to pluripotent ones has enormous potential not only as a tool to generate cells for disease therapy and modeling, but also as an experimental system to investigate fundamental biological questions. The discovery of mesenchymal-to-epithelial transitions at the initial phase of reprogramming provides a conceptual ...
Xiaodong, Shu, Duanqing, Pei
openaire   +2 more sources

Sox2 induces Mesenchymal to Epithelial transition in somatic cells

Italian Journal of Anatomy and Embryology, 2014
During late embryonic development mesodermal cells generate epithelial organs, such as kidney and ovary, via a process named Mesenchymal to Epithelial Transition (MET) (1). This process can also occur reversely giving rise to Epithelial to Mesenchimal transition (EMT) (2), which represents the mechanism by which metastasis originate from primary tumors.
Federica Campolo, Susanna Dolci
openaire   +1 more source

The many regulators of epithelial−mesenchymal transition

Nature Reviews Molecular Cell Biology, 2021
Cameron Bracken, Gregory J Goodall
exaly  

[Advances in mesenchymal to epithelial transition factor signaling pathway and inhibitors].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2019
As a receptor tyrosine kinase, mesenchymal to epithelial transition factor (MET) is the membrane receptor for hepatocyte growth factor (HGF), which is related with a series of biological functions, such as cell proliferation, progression, apoptosis, metastasis and morphological changes. As research continues, MET is amplified or overexpressed in a wide
Jiangjun, Cao   +5 more
openaire   +1 more source

The amoeboid state as part of the epithelial-to-mesenchymal transition programme

Trends in Cell Biology, 2022
Oscar Maiques   +2 more
exaly  

Guidelines and definitions for research on epithelial–mesenchymal transition

Nature Reviews Molecular Cell Biology, 2020
Antonio García de Herreros   +2 more
exaly  

New insights into the mechanisms of epithelial–mesenchymal transition and implications for cancer

Nature Reviews Molecular Cell Biology, 2018
Anushka Dongre, Robert Weinberg
exaly  

Epithelial–mesenchymal transitions in human breast cancer samples

Nature Reviews Clinical Oncology, 2013
Vanessa Marchesi
exaly  

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