Results 91 to 100 of about 556,462 (362)

Effect of Platelet-rich Plasma and Mesenchymal Stem Cells as Two Biological Alternatives in Rotator Cuff Injury Treatment: A Mini-review

Research in Molecular Medicine, 2019
The rotator cuff injury is caused by significant damage by trauma or other factors and currently recognized as a prevalent orthopedic problem. Many clinical procedures have been proposed to reduce the complication of rotator cuff injury with varying ...
Mohsen Sheykhhasan, Hamed Manoochehri, Pouria Samadi, Reza Fotouhi-Ardakani, Naser Kalhor   +4 more
doaj  

Induced pluripotent stem cell–derived mesenchymal stem cells enhance acellular nerve allografts to promote peripheral nerve regeneration by facilitating angiogenesis

Neural Regeneration Research
Previous research has demonstrated the feasibility of repairing nerve defects through acellular allogeneic nerve grafting with bone marrow mesenchymal stem cells. However, adult tissue–derived mesenchymal stem cells encounter various obstacles, including
Fan-Qi Meng, Chao-Chao Li, Wen-Jing Xu, Jun-Hao Deng, Yan-Jun Guan, Tie-Yuan Zhang, Bo-Yao Yang, Jian Zhang, Xiang-Ling Li, Feng Han, Zhi-Qi Ren, Shuai Xu, Yan Liang, Wen Jiang, Jiang Peng, Yu Wang, Hai-Ying Liu   +16 more
doaj   +1 more source

ADMINISTRATION OF BONE MARROW DERIVED MESENCHYMAL STEM CELLS MODULATE TLR EXPRESSION DURING LIVER REGENERATION

Trakya University Journal of Natural Sciences, 2019
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel, Kamil Can Akçalı, Burcu İnsal, Hande Kocak, Zeynep Tokcaer-keskin   +4 more
doaj   +1 more source

Comments on: “Mesenchymal stem cells transplantation for perianal fistulas: a systematic review and meta-analysis of clinical trials”

Stem Cell Research & Therapy, 2023
The meta-analysis by Wang et al. (Stem Cell Res Ther 14(1):103, 2023) aims to explore whether mesenchymal stem cells are effective for perianal fistulas.
Fang Cheng
doaj   +1 more source

Dental mesenchymal stem cells [PDF]

Development, 2016
Mammalian teeth harbour mesenchymal stem cells (MSCs), which contribute to tooth growth and repair. These dental MSCs possess many in vitro features of bone marrow-derived MSCs, including clonogenicity, expression of certain markers, and following stimulation, differentiation into cells that have the characteristics of osteoblasts, chondrocytes and ...
openaire   +3 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Role of miRNAs from mesenchymal stem cell–derived extracellular vesicles in neuroinflammation and behavioral impairments induced by chronic alcohol consumption in female mice

Neural Regeneration Research
Mesenchymal stem cell–derived extracellular vesicles have emerged as a promising form of regenerative and immunomodulatory therapy; indeed, micro (mi)RNAs contained within mesenchymal stem cell–derived extracellular vesicles modulate target gene ...
Susana Mellado, Najoua Touahri, Sandra Montagud-Romero, Carla Perpiñá-Clérigues, Francisco García-García, Victoria Moreno-Manzano, Consuelo Guerri, Marta Rodríguez-Arias, María Pascual   +8 more
doaj   +1 more source

Mesenchymal Stem Cells Immunosuppressed IL-22 in Patients with Immune Thrombocytopenia via Soluble Cellular Factors

Journal of Immunology Research, 2015
Mesenchymal stem cells are immunoregulation cells. IL-22 plays an important role in the pathogenesis of immune thrombocytopenia. However, the effects of mesenchymal stem cells on IL-22 production in patients with immune thrombocytopenia remain unclear ...
Mei Wu, Hongfeng Ge, Shue Li, Hailiang Chu, Shili Yang, Xiaoxing Sun, Zhenxia Zhou, Xiongpeng Zhu   +7 more
doaj   +1 more source

Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition. [PDF]

, 2016
The epithelial-mesenchymal transition (EMT) endows carcinoma cells with phenotypic plasticity that can facilitate the formation of cancer stem cells (CSCs) and contribute to the metastatic cascade.
Banno, Asoka, Bui, Jack D, Chang, Aaron N, Chang, John T, Fisch, Kathleen, Florea, Bogdan I, Garcia, Daniel A, Geurink, Paul P, Kim, Stephanie H, Lopez, Justine, Metz, Patrick J, Ovaa, Huib, Overkleeft, Hermen S, van Baarsel, Eric D, Widjaja, Christella E, Yang, Jing   +15 more
core   +2 more sources

Therapeutic Potential of Mesenchymal Stem Cells for Cancer Therapy [PDF]

, 2020
Mesenchymal stem cells (MSCs) are among the most frequently used cell type for regenerative medicine. A large number of studies have shown the beneficial effects of MSC-based therapies to treat different pathologies, including neurological disorders ...
Capilla González, Vivian, Gauthier, Benoit R., Hmadcha, Abdelkrim, Martín Montalvo, Alejandro, Soria Escoms, Bernat   +4 more
core   +1 more source