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Mesenchymal stem cells and their microenvironment
Mesenchymal stem cells (MSC) are multipotent stem cells that hold promise for an expanding list of therapeutic uses, not only due to their ability to differentiate into all connective tissues including bone, fat and cartilage, but additionally due to their trophic and anti-inflammatory effects which contribute to healing and tissue regeneration ...
Richard G. DiScipio +2 more
openaire +3 more sources
Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja +22 more
core +1 more source
Current status and potential challenges of mesenchymal stem cell-based therapy for malignant gliomas
Glioma, which accounts for more than 30% of primary central nervous system tumours, is characterised by symptoms such as headaches, epilepsy, and blurred vision. Glioblastoma multiforme is the most aggressive, malignant, and lethal brain tumour in adults.
Qing Zhang +9 more
semanticscholar +1 more source
Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell [PDF]
S. Jena +3 more
openalex +1 more source
Focus on Mesenchymal Stem Cell-Derived Exosomes: Opportunities and Challenges in Cell-Free Therapy
Mesenchymal stem cells have been at the forefront of regenerative medicine for many years. Exosomes, which are nanovesicles involved in intercellular communication and the transportation of genetic material transportation that can be released by ...
Lin Cheng +4 more
semanticscholar +1 more source
Rigidity of silicone substrates controls cell spreading and stem cell differentiation. [PDF]
The dependences of spreading and differentiation of stem cells plated on hydrogel and silicone gel substrates on the rigidity and porosity of the substrates have recently been a subject of some controversy.
Groisman, Alex +5 more
core +2 more sources
Pluronic F-127 hydrogel as a promising scaffold for encapsulation of dental-derived mesenchymal stem cells [PDF]
Diniz, Ivana MA +7 more
openalex +1 more source
Evidence has emerged that stem cells represent a promising therapeutic tool for tissue engineering and regenerative medicine. Thus, identifying functional markers for selecting stem cells capable of superior self-renewal and pluripotency (or multipotency)
Chiao-Fang Teng +2 more
doaj +1 more source

