Results 141 to 150 of about 288,005 (268)

Mesenchymal Stem Cell Therapy for Neurological Complications of Prematurity: A Narrative Review. [PDF]

Pharmaceuticals (Basel)
Yep HH, Bae JH, Wen GA, Gomez S, Tsivitis A, Moore RP, Hsieh H, Bergese SD.   +7 more
europepmc   +1 more source

Developmentally Inspired Bioprinting of Nascent Multicellular Human Heart Tissue Through in Situ Differentiation and Morphogenesis of iPSCs

Advanced Science, EarlyView.
A developmentally inspired bioprinting approach enables the fabrication of pluripotent tissues that undergo shape‐morphing and in situ cardiac lineage specification. This method employs embedded bioprinting to deposit iPSCs within soft granular hydrogels to create pluripotent tissue constructs that undergo cell‐mediated shape morphogenesis.
Ankita Pramanick, Juhi Chakraborty, Orlaith Kennedy, Hey Wei Wong, Sogol Kianersi, Daniel Kelly, Vasileios Sergis, Abhay Pandit, Andrew C. Daly   +8 more
wiley   +1 more source

Effective Recellularization Using Mesenchymal Stem Cell Monoculture for Next-Generation Heart Valves. [PDF]

Bioengineering (Basel)
Kim SY, Yoon JK, Kim S, Ko S, Shin Y, Kim GB, Lim HG, Kim YJ.   +7 more
europepmc   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Production and Purification of Mesenchymal Stem Cell-Derived Extracellular Vesicles Using Preferential Exclusion Chromatography. [PDF]

Electrophoresis
Vrabec K, Raspor A, Božič D, Bizjak Ternik N, Železnik A, Novak V, Petrović Koshmak I, Leskovec M, Štrancar A.   +8 more
europepmc   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

Advanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen, Yuman Li, Chenyu Deng, Leran Li, Zhewen Hu, Boon Chin Heng, Yuting Niu, Shiyu Sun, Min Gao, Xiaopei Chi, Ying He, Mingming Xu, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Induction of Mesenchymal Stem Cell and Preosteoblast Differentiation: A Comparative Study Between Conditioned Medium and In Vitro Coculture. [PDF]

Int J Dent
Escobar LM, Bendahan Z, Lugo W, Calderón E, Ramirez LE, Castaño S, Castellanos JE, Gonzalez-Carrera MC.   +7 more
europepmc   +1 more source

Harnessing MDM2‐Mediated Targeted Degradation of Transcriptional and Epigenetic Machinery to Disrupt Oncogenic Addictions in Pediatric Sarcoma

Advanced Science, EarlyView.
MDM2 dependency in pediatric sarcomas is driven by a novel p53‐independent oncogenic cistrome alongside canonical p53 pathway suppression. This study introduces MDM2‐recruiting transcriptional and epigenetic machinery degraders (MDM2‐TEMADs) as a novel precision oncology modality.
Jiawei Zhou, Xian Guan, Nan Li, Ying Zhang, Long Xie, Xingze Huang, Zhipeng Zhu, Zhuolin Ren, Xiaoyan Yu, Hanjun Guo, Yuanfang Wu, Lin Ma, Suya Zheng, Jingyao Zhang, Jiyang Liu, Victor Kuanmin Lee, Wenhao Chen, H. Phillip Koeffler, Jinhu Wang, Xin Han, Ye Chen, Liang Xu   +21 more
wiley   +1 more source

Effects of mesenchymal stem cell secretome on osteoclast- and osteogenesis-related markers during orthodontic relapse. [PDF]

J Taibah Univ Med Sci
Pramusita A, Narmada IB, Winoto ER, Alida A, Pratiwi FDA, Zaky LF, Triwardhani A, Ardani IGAW, Riawan W, Novianti D, Putranti NAR, Putranto AF, Noor TNEBTA, Nugraha AP.   +13 more
europepmc   +1 more source

Disruption of the SNRPF–DDX24–E2F4 Feedback Loop Uncouples Splicing and Transcriptional Regulation to Suppress Ovarian Cancer Progression

Advanced Science, EarlyView.
This study identifies SNRPF as a critical oncogenic driver in ovarian cancer. By regulating a self‐sustaining SNRPF–DDX24–E2F4 feedback loop through intron retention and nonsense‐mediated decay, SNRPF couples RNA splicing with transcriptional regulation to promote tumor progression.
Yingwei Li, Zhongshao Chen, Qianqian Gao, Yuehan Gao, Ning Yang   +4 more
wiley   +1 more source