Results 141 to 150 of about 421,152 (353)
"Studies on the cardiomyocytic potential of dermal stem cells” [PDF]
, 2008 In Europe, diseases of the heart and circulatory system are the main cause of death; 48% of all deaths are from coronary heart disease, accounting for over 4.30 million deaths each year (European cardiovascular disease statistics 2008). Identifying stem
Cormack, Suzanne Marie
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Different approaches for transformation of mesenchymal stem cells into hepatocyte-like cells
Stem Cell Research & Therapy, 2020 Due to the prominent role of the liver in the body and detoxification, its functionality can be affected in an irreversible manner by diseases. This phenomenon renders the liver to stop working, leading to morbidity and mortality.
Afsoon Afshari +4 more
doaj +1 more source
Advanced Science, EarlyView.Brown adipocyte sheets are engineered to protect the heart against myocardial ischemia–reperfusion injury by restraining ferroptosis. Upon transplantation onto the cardiac surface, they improve cardiac function, limit infarction and fibrosis, and enhance angiogenesis.
Lifu Sun +6 more
wiley +1 more source
A Comparison of Equine Adipose Tissue, Bone Marrow and Peripheral Blood as Sources of Mesenchymal Stem Cells [PDF]
, 2014 Lameness is a significant cause of wastage in equine athletes, with reportedly 66% days lost from training being contributed to musculoskeletal injuries.
Redmond Hubbard, Amy Louise
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Hematology, Transfusion and Cell TherapyIntroduction: Multipotent mesenchymal stromal cells are progenitors of the bone marrow stromal microenvironment that support hematopoiesis. Mitochondria, which can be transferred between cells via nanotubes or extracellular vesicles, play a key role in ...
Natalya Sats +11 more
doaj +1 more source
Stem cell research & therapeutics, 2014 IntroductionStem cell therapy has recently been introduced to treat patients with type 2 diabetes mellitus (T2DM). However, no data are available on the efficacy and safety of allogeneic Wharton’s Jelly-derived mesenchymal stem cell (WJ-MSC ...
Xue-bin Liu +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Investigating the properties of cancer stem cells and epithelial to mesenchymal transition in human prostate cancer [PDF]
, 2012 In recent years, the cancer stem cell hypothesis has emerged as a compelling but controversial model of cancer progression. Contrary to the clonal evolution model, the cancer stem cell hypothesis postulates that, akin to normal tissues, tumours are ...
Dunning-Foreman, NL
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Neural Regeneration Research, 2014 In the present study, we transplanted adipose-derived mesenchymal stem cells into the hippocampi of APP/PS1 transgenic Alzheimer's disease model mice.
Yufang Yan +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng +10 more
wiley +1 more source