Results 171 to 180 of about 139,532 (214)
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Mesenchymal Stem Cells and Hematopoietic Stem Cell Transplantation
Annals of the New York Academy of Sciences, 2003Abstract: Techniques have recently beome available to isolate and grow mesenchymal progenitors and to manipulate their growth under defined in vitro culture conditions. As a result mesenchymal stem cells can be rapidly expanded to numbers that are required for clinical application.
Willem E, Fibbe, Willy A, Noort
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Current Opinion in Organ Transplantation, 2012
Mesenchymal stem or stromal cells (MSCs) are multipotent cells with immunomodulatory and regenerative capacities. These properties make MSCs interesting for use as a cell therapeutic agent in solid-organ transplantation (SOT). Their applicability in SOT has recently been evaluated in numerous preclinical and clinical studies, which are reviewed in this
Rhijn, Marieke +2 more
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Mesenchymal stem or stromal cells (MSCs) are multipotent cells with immunomodulatory and regenerative capacities. These properties make MSCs interesting for use as a cell therapeutic agent in solid-organ transplantation (SOT). Their applicability in SOT has recently been evaluated in numerous preclinical and clinical studies, which are reviewed in this
Rhijn, Marieke +2 more
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Mesenchymal stromal cells and hematopoietic stem cell transplantation
Immunology Letters, 2015Mesenchymal stromal cells (MSCs) comprise a heterogeneous population of multipotent cells that can be isolated from various human tissues and culture-expanded ex vivo for clinical use. Due to their immunoregulatory properties and their ability to secrete growth factors, MSCs play a key role in the regulation of hematopoiesis and in the modulation of ...
Bernardo, M.E., Fibbe, W.E.
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Mesenchymal stem cells and haematopoietic stem cell transplantation
Best Practice & Research Clinical Haematology, 2004The bone marrow serves as a reservoir for different classes of stem cells. In addition to haemopoietic stem cells, the bone marrow comprises a population of marrow stromal cells or mesenchymal stem cells (MSCs). These cells exhibit multilineage differentiation capacity, and are able to generate progenitors with restricted developmental potential ...
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Mesenchymal Stromal Cells in Hematopoietic Stem Cell Transplantation
2016Mesenchymal stromal cells (MSCs) comprise a heterogeneous population of multipotent cells that can be isolated from various human tissues and cultured ex vivo for clinical use. Thanks to their secretion of growth factors, immunomodulatory properties and cell-to-cell interactions, MSCs play a key role in the regulation of hematopoiesis and in the ...
Bernardo M. E., Locatelli F.
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Role of mesenchymal stem cells in hematopoietic stem cell transplantation
Current Opinion in Hematology, 2000Within the bone marrow stroma are multipotential cells which are capable of differentiation into a number of mesenchymal cell lineages. These cells, termed mesenchymal stem cells, have recently been identified and characterized in humans. Many studies indicate that the bone marrow stroma is damaged following bone marrow transplantation.
S M, Devine, R, Hoffman
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Lupus, 2018
Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disorder with involvement of several organs and systems such as the kidney, lung, brain and the hematopoietic system. As the most prevailing organ manifestation, lupus nephritis is the major cause of mortality and morbidity in SLE patients.
A, Fathollahi, N B, Gabalou, S, Aslani
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Systemic lupus erythematosus (SLE) is a chronic autoimmune and inflammatory disorder with involvement of several organs and systems such as the kidney, lung, brain and the hematopoietic system. As the most prevailing organ manifestation, lupus nephritis is the major cause of mortality and morbidity in SLE patients.
A, Fathollahi, N B, Gabalou, S, Aslani
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Mesenchymal stem cells transplantation for systemic lupus erythematosus
International Journal of Rheumatic Diseases, 2015AbstractMesenchymal stem cells are a rare subset of stem cells residing in the bone marrow where they closely interact with hematopoietic stem cells and support their growth and differentiation. They can suppress proliferation or functions of many immune cells such as T cells, B cells, natural killer cells and dendritic cells.
Jun, Liang, Lingyun, Sun
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Mesenchymal Stem Cells and Transplantation Tolerance
2017Transplantation tolerance meaning stable graft function without rejection episodes in the absence of immunosuppressive drugs while maintaining third-party immune response intact is still not achieved in clinic. Mesenchymal stem cells (MSCs) are believed to fulfill this dream of tolerance due to their immunomodulatory and tolerogenic properties.
Hargovind L. Trivedi, Aruna V. Vanikar
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Transplantation of Mesenchymal Stem Cells in Multiple Sclerosis
Neuroscience and Behavioral Physiology, 2012To assess safety and tolerability of treatment with autologic multipotent mesenchymal stem cells (MSC) in multiple sclerosis (MS), we have obtained autologic red bone marrow-derived MSC from 8 patients. Proliferation, immunophenotype and caryotype of MSC, their sterility, the absence of hemopoetic cells, chromosomal aberrations and signs of aging were ...
M M, Odinak +7 more
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