Results 61 to 70 of about 139,532 (214)

Dose-Independent Therapeutic Benefit of Bone Marrow Stem Cell Transplantation after MI in Mice

Biomedicines, 2020
Several cell populations derived from bone marrow (BM) have been shown to possess cardiac regenerative potential. Among these are freshly isolated CD133+ hematopoietic as well as culture-expanded mesenchymal stem cells. Alternatively, by purifying CD271+
Nicole Zarniko, Anna Skorska, Gustav Steinhoff, Robert David, Ralf Gaebel   +4 more
doaj   +1 more source

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor [PDF]

, 2018
derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focussed on
A Augello, AJ Nauta, AJ Poncelet, AJ White, AS Boyd, B Hegyi, B Nadal-Ginard, C Basso, C Boriesson, C Liang, CH Chen, CY Xiao, D Carrade, D Pinheiro, DR Davis, DY Nah, E Ingulli, EM Oxford, G Couto de, G Wess, G Wess, GO Ramirez-Yañez, H Kanazawa, H Takeyama, I Chimenti, JA Dixon, JG Bartolucci, JM Angles, JW Kang, K Blanc Le, K Malliaras, K Malliaras, K Sato, KM Meurs, L Cambier, L Grigorian-Shamagian, L Lauden, L Öberg, LC Dutton, LJ Kennedy, M Haidar, MA Aminzadeh, MD Nicola, ME Bernardo, ME Campian, MM Duffy, MT Hensley, MT Hensley, N Kvirkvelia, O Campuzano, P Ross, PV Johnston, Q Guan, R Gallet, R Meisel, R Ramasamy, RR Makkar, S Aggarwal, S Simpson, SJ Jansen of Lorkeers, SR Houser, ST Lee, T Maślanka, TL Lynch, TS Li, WS Lee, Y Ding, Y Sun, YC Hsueh, Z Yan   +69 more
core   +2 more sources

Mesenchymal stem cell–derived small extracellular vesicles enhance the therapeutic effect of retinal progenitor cells in retinal degenerative disease rats

Neural Regeneration Research
Our previous study demonstrated that combined transplantation of bone marrow mesenchymal stem cells and retinal progenitor cells in rats has therapeutic effects on retinal degeneration that are superior to transplantation of retinal progenitor cells ...
Chunge Ren, Min Chen, Bangqi Ren, Yuxiao Zeng, Qiang Tan, Qiyou Li, Xue Zhang, Yajie Fang, Yixiao Zhou, Weitao Zhang, Fang Chen, Baishijiao Bian, Yong Liu   +12 more
doaj   +1 more source

Transplantation of mesenchymal stem cells in ALS

, 2012
Amyotrophic lateral sclerosis (ALS) is a devastating incurable, neurodegenerative disease that targets motor neurons (MNs) in the primary motor cortex, brainstem, and spinal cord, leading to muscle atrophy, paralysis, and death due to respiratory failure within 2-5 years. Currently, there is no cure for ALS.
Mazzini, Letizia, Vercelli, Alessandro, Ferrero, Ivana, Boido, Marina, Cantello, Roberto, Fagioli, Franca   +5 more
openaire   +3 more sources

Mesenchymal stem cells for kidney transplantation

World Journal of Clinical Urology, 2014
Published online: July 24, 2014 ; The long term consequence of immunosuppressive therapy in kidney transplantation has prompted investigation of alternative means to modify the immune response to the allograft. Cell based therapies are potentially attractive as they may provide a long lasting immunomodulatory effect, may repair tissues and reduce the ...
Lett, B., Sivanathan, K., Coates, P.
openaire   +2 more sources

Mesenchymal stem cell-based therapy in kidney transplantation [PDF]

Stem Cell Research & Therapy, 2016
AbstractKidney transplantation is the best treatment for end-stage renal disease, but its implementation is limited by organ shortage and immune rejection. Side effects of current immunosuppressive drugs, such as nephrotoxicity, opportunistic infection, and tumorigenic potential, influence long-term graft outcomes.
Chen, Cheng, Hou, Jianquan
openaire   +2 more sources

Transplantation of human umbilical cord mesenchymal stem cells to treat premature ovarian failure

Stem Cell Research & Therapy, 2021
As one of the problems and diseases for women before 40 years, premature ovarian failure (POF) could be characterized by amenorrhea, low estrogen levels, infertility, high gonadotropin levels, and lack of mature follicles.
Oldouz Shareghi-oskoue, Leili Aghebati-Maleki, Mehdi Yousefi   +2 more
doaj   +1 more source

Co-transplantation of mesenchymal stem cells improves spermatogonial stem cell transplantation efficiency in mice [PDF]

Yearbook of Paediatric Endocrinology, 2018
Spermatogonial stem cell transplantation (SSCT) could become a fertility restoration tool for childhood cancer survivors. However, since in mice, the colonization efficiency of transplanted spermatogonial stem cells (SSCs) is only 12%, the efficiency of the procedure needs to be improved before clinical implementation is possible. Co-transplantation of
Prashant Kadam, Elissavet Ntemou, Yoni Baert, Sven Van Laere, Dorien Van Saen, Ellen Goossens   +5 more
openaire   +5 more sources

Mesenchymal stem cells in craniofacial reconstruction: a comprehensive review

Frontiers in Molecular Biosciences
Craniofacial reconstruction faces many challenges, including high complexity, strong specificity, severe injury, irregular and complex wounds, and high risk of bleeding.
Zizhuo Zheng, Hanghang Liu, Shibo Liu, En Luo, Xian Liu   +4 more
doaj   +1 more source

iPSC-derived mesenchymal stem cells attenuate cerebral ischemia-reperfusion injury by inhibiting inflammatory signaling and oxidative stress

Molecular Therapy: Methods & Clinical Development, 2023
Induced pluripotent stem cell-derived mesenchymal stem cells (iMSCs) hold great promise as a cell source for transplantation into injured tissues to alleviate inflammation.
Masafumi Arakawa, Yuki Sakamoto, Yoshitaka Miyagawa, Chikako Nito, Shiro Takahashi, Yuko Nitahara-Kasahara, Satoshi Suda, Yoshiyuki Yamazaki, Mashito Sakai, Kazumi Kimura, Takashi Okada   +10 more
doaj   +1 more source