Results 41 to 50 of about 5,762,651 (303)

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study. [PDF]

, 2012
BACKGROUND: More than half of patients with multiple sclerosis have progressive disease characterised by accumulating disability. The absence of treatments for progressive multiple sclerosis represents a major unmet clinical need.
Kolappan, Madhan, Thompson, Alan J, Luan, Shi-Lu, Altmann, Daniel R, Crawley, Charles, Compston, Alastair, Patani, Rickie, Scott, Michael A, Du, Ming-Qing, Miller, David H, Michell, Andrew W, Chandran, Siddharthan, Connick, Peter, Webber, Daniel J   +13 more
core   +1 more source

Novel therapeutic strategies for injured endometrium: intrauterine transplantation of menstrual blood‑derived cells from infertile patients

Stem Cell Research & Therapy, 2023
Background Menstrual blood-derived cells show regenerative potential as a mesenchymal stem cell and may therefore be a novel stem cell source of treatment for refractory infertility with injured endometrium.
Satoshi Hosoya, Ryo Yokomizo, Harue Kishigami, Yukiko Fujiki, Erika Kaneko, Mitsuyoshi Amita, Takakazu Saito, Hiroshi Kishi, Haruhiko Sago, Aikou Okamoto, Akihiro Umezawa   +10 more
doaj   +1 more source

Alginate Scaffolds for Mesenchymal Stem Cell Cardiac Therapy: Influence of Alginate Composition [PDF]

, 2012
Despite the success of alginate scaffolds and mesenchymal stem cells (MSCs) therapy in cardiac failure treatment, the impact of the physicochemical environment provided by alginate matrices on cell behavior has never been investigated.
Alfarano, Chiara, Ceccaldi, Caroline, Calise, Denis, Sallerin, Brigitte, Girod Fullana, Sophie, Cussac, Daniel, Parini, Angelo, Lairez, Olivier   +7 more
core   +1 more source

ADMINISTRATION OF BONE MARROW DERIVED MESENCHYMAL STEM CELLS MODULATE TLR EXPRESSION DURING LIVER REGENERATION

Trakya University Journal of Natural Sciences, 2019
Liver cell transplantation is a powerful alternative to orthotopic cell transplantation in the treatment of liver failures. Recently, considerable effort is being channeled to understand the nature and kinetics of directing stem cells to effectively ...
İhsan Gursel, Kamil Can Akçalı, Burcu İnsal, Hande Kocak, Zeynep Tokcaer-keskin   +4 more
doaj   +1 more source

Melatonin, tunneling nanotubes, mesenchymal cells, and tissue regeneration

Neural Regeneration Research, 2023
Mesenchymal stem cells are multipotent stem cells that reside in many human tissues and organs. Mesenchymal stem cells are widely used in experimental and clinical regenerative medicine due to their capability to transdifferentiate into various lineages.
Francesca Luchetti, Silvia Carloni, Maria G Nasoni, Russel J Reiter, Walter Balduini   +4 more
doaj   +1 more source

[Mesenchymal stem cell therapy in hematopoietic stem cell transplantation].

[Rinsho ketsueki] The Japanese journal of clinical hematology, 2018
Mesenchymal stem cells (MSCs) have received considerable attention in allogeneic hematopoietic cell transplantation because of their abilities to modulate immune responses and promote hematopoiesis. Because MSCs are capable of producing several cytokines and growth factors, they have been widely used in the treatment of graft-versus-host disease (GVHD).
GOTO, Tatsunori, MURATA, Makoto
openaire   +2 more sources

Propofol combined with bone marrow mesenchymal stem cell transplantation improves electrophysiological function in the hindlimb of rats with spinal cord injury better than monotherapy

Neural Regeneration Research, 2015
The repair effects of bone marrow mesenchymal stem cell transplantation on nervous system damage are not satisfactory. Propofol has been shown to protect against spinal cord injury. Therefore, this study sought to explore the therapeutic effects of their
Yue-xin Wang, Jing-jing Sun, Mei Zhang, Xiao-hua Hou, Jun Hong, Ya-jing Zhou, Zhi-yong Zhang   +6 more
doaj   +1 more source

Donor mesenchymal stem cells trigger chronic graft-versus-host disease following minor antigen-mismatched bone marrow transplantation [PDF]

, 2012
Chronic graft-versus-host disease (cGVHD) is a complication after minor antigen mismatched bone marrow transplantation (BMT) characterized by an autoimmune-type reaction in various organs.
Yumi Matsuzaki, Yoko Ogawa, Shigeto Shimmura, Yo Mabuchi, Sadafumi Suzuki, Yutaka Kawakami, Shinichiro Okamoto, Hideyuki Okano, Takaaki Inaba, Satoru Morikawa, Saori Yaguchi, Kazuo Tsubota, Tomonori Yaguchi   +12 more
core  

Regulatory immune cells in transplantation. [PDF]

, 2012
Immune regulation is fundamental to any immune response to ensure that it is appropriate for the perceived threat to the host. Following cell and organ transplantation, it is essential to control both the innate immune response triggered by the injured ...
Bushell, Andrew, Wood, Kathryn, Bushell, A, Hester, J, Wood, Kathryn J, Andrew Bushell, Joanna Hester, Kathryn J. Wood, Wood, KJ, Hester, Joanna   +9 more
core   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source