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Testosterone Propionate Promotes Proliferation and Viability of Bone Marrow Mesenchymal Stem Cells while Preserving Their Characteristics and Inducing Their Anti-Cancer Efficacy

open access: yesBalkan Medical Journal, 2023
Background: Various studies have reported the effects of testosterone on different cell types, yet bone marrow-derived mesenchymal stem cells’ cellular responses to testosterone remain unknown. Aims: To investigate the effects of testosterone propionate,
Başak Aru   +4 more
doaj   +1 more source

Bone regeneration capacities of alveolar bone mesenchymal stem cells sheet in rabbit calvarial bone defect

open access: yesJournal of Tissue Engineering, 2020
Mesenchymal stem cells sheets have been verified as a promising non-scaffold strategy for bone regeneration. Alveolar bone marrow mesenchymal stem cells, derived from neural crest, have the character of easily obtained and strong multi-differential ...
Yanan Liu   +7 more
doaj   +1 more source

Feasibility of bone marrow mesenchymal stem cells harvesting from forearm bone

open access: yesHeliyon, 2021
Introduction: Mesenchymal stem cell is a promising therapeutic option in orthopedic filed and regenerative medicine. The feasibility of isolation method and characterization of Mesenchymal stem cell including growth kinetics, immunophenotypes and ...
Tulyapruek Tawonsawatruk   +4 more
doaj   +1 more source

GATA2 regulates differentiation of bone marrow-derived mesenchymal stem cells

open access: yesHaematologica, 2014
The bone marrow microenvironment comprises multiple cell niches derived from bone marrow mesenchymal stem cells. However, the molecular mechanism of bone marrow mesenchymal stem cell differentiation is poorly understood. The transcription factor GATA2 is
Mayumi Kamata   +12 more
doaj   +1 more source

Macrophages—bone marrow mesenchymal stem cells crosstalk in bone healing

open access: yesFrontiers in Cell and Developmental Biology, 2023
Bone healing is associated with many orthopedic conditions, including fractures and osteonecrosis, arthritis, metabolic bone disease, tumors and periprosthetic particle-associated osteolysis.
Siyu Fan   +10 more
doaj   +1 more source

Gender difference in the neuroprotective effect of rat bone marrow mesenchymal cells against hypoxia-induced apoptosis of retinal ganglion cells

open access: yesNeural Regeneration Research, 2016
Bone marrow mesenchymal stem cells can reduce retinal ganglion cell death and effectively prevent vision loss. Previously, we found that during differentiation, female rhesus monkey bone marrow mesenchymal stem cells acquire a higher neurogenic potential
Jing Yuan, Jian-xiong Yu
doaj   +1 more source

MicroRNA changes of bone marrow-derived mesenchymal stem cells differentiated into neuronal-like cells by Schwann cell-conditioned medium

open access: yesNeural Regeneration Research, 2019
Bone marrow-derived mesenchymal stem cells differentiate into neurons under the induction of Schwann cells. However, key microRNAs and related pathways for differentiation remain unclear.
Zhi-Jian Wei   +11 more
doaj   +1 more source

Biological conduits combining bone marrow mesenchymal stem cells and extracellular matrix to treat long-segment sciatic nerve defects

open access: yesNeural Regeneration Research, 2015
The transplantation of polylactic glycolic acid conduits combining bone marrow mesenchymal stem cells and extracellular matrix gel for the repair of sciatic nerve injury is effective in some respects, but few data comparing the biomechanical factors ...
Yang Wang   +4 more
doaj   +1 more source

Comparison of senescence phenotype of short- and long- term cultured rat mesenchymal stem cells in vitro [PDF]

open access: yesAnais da Academia Brasileira de Ciências, 2022
Mesenchymal stem cells present clinical potential to recover and regenerate injured tissues in diverse pathologies. The in vitro expansion and characterization of these cells contribute to elucidation of the mechanisms of senescence and strategies ...
VANESSA P.A. LEMOS   +7 more
doaj   +1 more source

Bone marrow mesenchymal stem cells from patients with aplastic anemia maintain functional and immune properties and do not contribute to the pathogenesis of the disease

open access: yesHaematologica, 2014
Aplastic anemia is a life-threatening bone marrow failure disorder characterized by peripheral pancytopenia and marrow hypoplasia. The majority of cases of aplastic anemia remain idiopathic, although hematopoietic stem cell deficiency and impaired immune
Clara Bueno   +13 more
doaj   +1 more source

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