Results 21 to 30 of about 125,148 (266)

Collagen-chitosan scaffold impregnated with bone marrow mesenchymal stem cells for treatment of traumatic brain injury

open access: yesNeural Regeneration Research, 2019
Combinations of biomaterials and cells can effectively target delivery of cells or other therapeutic factors to the brain to rebuild damaged nerve pathways after brain injury.
Feng Yan   +9 more
doaj   +1 more source

Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies

open access: yesNeural Regeneration Research, 2016
Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood.
Guihong Li   +7 more
doaj   +1 more source

Comparison of Human Adipose-Derived Stem cells and Bone Marrow-Derived Stem cells in a Myocardial Infarction Model

open access: yesCell Transplantation, 2014
Treatment of myocardial infarction (MI) with bone marrow-derived mesenchymal stem cells and recently also adipose-derived stem cells has shown promising results.
Jeppe Grøndahl Rasmussen   +7 more
doaj   +1 more source

Dorsal root ganglion neurons promote proliferation and osteogenic differentiation of bone marrow mesenchymal stem cells

open access: yesNeural Regeneration Research, 2015
Preliminary animal experiments have confirmed that sensory nerve fibers promote osteoblast differentiation, but motor nerve fibers have no promotion effect.
Pei-xun Zhang   +5 more
doaj   +1 more source

Sensory nerves in the spotlight of the stem cell niche

open access: yesStem Cells Translational Medicine, 2021
Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life ...
Caroline C. Picoli   +13 more
doaj   +1 more source

Bone Marrow: The Central Immune System

open access: yesImmuno, 2023
Bone marrow is known as the site of hematopoiesis. What is not being described in textbooks of immunology is the fact that bone marrow is not only a generative, but also an antigen-responsive, immune organ.
Volker Schirrmacher
doaj   +1 more source

Phenotypic and Functional Equivalency of Digested Bone Marrow Mesenchymal Stem Cells to Aspirated Bone Marrow Mesenchymal Stem Cells

open access: yesThe FASEB Journal, 2019
Adult mesenchymal stem cells (MSCs) are found throughout the body, including in the dental pulp, adipose tissue, and bone marrow (BM), among other tissues. MSCs are receiving increased attention in the medical field due to their therapeutic and regenerative effects.
Hannah Marie Miller   +5 more
openaire   +1 more source

TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow

open access: yesStem Cell Reports, 2019
Summary: Mesenchymal stromal cells are key components of hematopoietic niches in the bone marrow. Here we abrogated transforming growth factor β (TGF-β) signaling in mesenchymal stem/progenitor cells (MSPCs) by deleting Tgfbr2 in mesenchymal cells using ...
Grazia Abou-Ezzi   +8 more
doaj   +1 more source

Mitophagy promotes the stemness of bone marrow-derived mesenchymal stem cells

open access: yesExperimental Biology and Medicine, 2020
Previous studies demonstrated that mitochondrial fission arguments the stemness of bone marrow-derived mesenchymal stem cells (BMSCs). Because mitophagy is critical in removing damaged or surplus mitochondrial fragments and maintaining mitochondrial integrity, the present study was undertaken to test the hypothesis that mitophagy is involved in ...
Xiaorong Feng   +4 more
openaire   +3 more sources

Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair [PDF]

open access: yesStem Cells International, 2013
Mesenchymal stem cells (MSCs) are prototypical adult stem cells with the capacity for self-renewal and differentiation with a broad tissue distribution. MSCs not only differentiate into types of cells of mesodermal lineage but also into endodermal and ectodermal lineages such as bone, fat, cartilage and cardiomyocytes, endothelial cells, lung ...
Ming Li, Susumu Ikehara
openaire   +3 more sources

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