Results 21 to 30 of about 125,148 (266)
Combinations of biomaterials and cells can effectively target delivery of cells or other therapeutic factors to the brain to rebuild damaged nerve pathways after brain injury.
Feng Yan +9 more
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Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood.
Guihong Li +7 more
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Treatment of myocardial infarction (MI) with bone marrow-derived mesenchymal stem cells and recently also adipose-derived stem cells has shown promising results.
Jeppe Grøndahl Rasmussen +7 more
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Preliminary animal experiments have confirmed that sensory nerve fibers promote osteoblast differentiation, but motor nerve fibers have no promotion effect.
Pei-xun Zhang +5 more
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Sensory nerves in the spotlight of the stem cell niche
Niches are specialized tissue microenvironments that control stem cells functioning. The bone marrow mesenchymal stem cell niche defines a location within the marrow in which mesenchymal stem cells are retained and produce new cells throughout life ...
Caroline C. Picoli +13 more
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Bone Marrow: The Central Immune System
Bone marrow is known as the site of hematopoiesis. What is not being described in textbooks of immunology is the fact that bone marrow is not only a generative, but also an antigen-responsive, immune organ.
Volker Schirrmacher
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Adult mesenchymal stem cells (MSCs) are found throughout the body, including in the dental pulp, adipose tissue, and bone marrow (BM), among other tissues. MSCs are receiving increased attention in the medical field due to their therapeutic and regenerative effects.
Hannah Marie Miller +5 more
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Summary: Mesenchymal stromal cells are key components of hematopoietic niches in the bone marrow. Here we abrogated transforming growth factor β (TGF-β) signaling in mesenchymal stem/progenitor cells (MSPCs) by deleting Tgfbr2 in mesenchymal cells using ...
Grazia Abou-Ezzi +8 more
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Mitophagy promotes the stemness of bone marrow-derived mesenchymal stem cells
Previous studies demonstrated that mitochondrial fission arguments the stemness of bone marrow-derived mesenchymal stem cells (BMSCs). Because mitophagy is critical in removing damaged or surplus mitochondrial fragments and maintaining mitochondrial integrity, the present study was undertaken to test the hypothesis that mitophagy is involved in ...
Xiaorong Feng +4 more
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Bone-Marrow-Derived Mesenchymal Stem Cells for Organ Repair [PDF]
Mesenchymal stem cells (MSCs) are prototypical adult stem cells with the capacity for self-renewal and differentiation with a broad tissue distribution. MSCs not only differentiate into types of cells of mesodermal lineage but also into endodermal and ectodermal lineages such as bone, fat, cartilage and cardiomyocytes, endothelial cells, lung ...
Ming Li, Susumu Ikehara
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