Results 31 to 40 of about 213,033 (265)

Multi-Parameter Analysis of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence for Donor Age and Mild Comorbidities on Phenotypic and Functional Properties [PDF]

, 2019
Heterogeneous populations of human bone marrow-derived stromal cells (BMSC) are among the most frequently tested cellular therapeutics for treating degenerative and immune disorders, which occur predominantly in the aging population.
Andrzejewska, Anastazja, Beez, Christien, Blankenstein, Antje, Catar, Rusan, Duda, Georg, Geissler, Sven, Jacobi, Dorit, Jürchott, Karsten, Kamhieh-Milz, Julian, Krüger, David, Krüger, Ulrike, Moll, Guido, Qazi, Taimoor Hasan, Reinke, Petra, Reinke, Simon, Richter, Sarina, Sass, Frauke Andrea, Schlickeiser, Stephan, Schoon, Janosch, Souidi, Naima, Streitz, Mathias, Strunk, Dirk, Zemojtel, Tomasz   +22 more
core   +1 more source

TGF-β Signaling Plays an Essential Role in the Lineage Specification of Mesenchymal Stem/Progenitor Cells in Fetal Bone Marrow

Stem Cell Reports, 2019
Summary: Mesenchymal stromal cells are key components of hematopoietic niches in the bone marrow. Here we abrogated transforming growth factor β (TGF-β) signaling in mesenchymal stem/progenitor cells (MSPCs) by deleting Tgfbr2 in mesenchymal cells using ...
Grazia Abou-Ezzi, Teerawit Supakorndej, Jingzhu Zhang, Bryan Anthony, Joseph Krambs, Hamza Celik, Darja Karpova, Clarissa S. Craft, Daniel C. Link   +8 more
doaj   +1 more source

Bone marrow mononuclear cells and acute myocardial infarction [PDF]

, 2012
PMCID: PMC3340546This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided ...
Arnous, S, Martin, J, Mathur, A, Mozid, A   +3 more
core   +1 more source

Repair of peripheral nerve defects with chemically extracted acellular nerve allografts loaded with neurotrophic factors-transfected bone marrow mesenchymal stem cells

Neural Regeneration Research, 2015
Chemically extracted acellular nerve allografts loaded with brain-derived neurotrophic factor-transfected or ciliary neurotrophic factor-transfected bone marrow mesenchymal stem cells have been shown to repair sciatic nerve injury better than chemically ...
Yan-ru Zhang, Ka Ka, Ge-chen Zhang, Hui Zhang, Yan Shang, Guo-qiang Zhao, Wen-hua Huang   +6 more
doaj   +1 more source

Rat bone marrow mesenchymal stem cells induced by rrPDGF-BB promotes bone regeneration during distraction osteogenesis

Frontiers in Bioengineering and Biotechnology, 2023
Background: In the clinical treatment of large bone defects, distraction osteogenesis can be used. However, some patients may suffer from poor bone regeneration, or even delayed healing or non-union.
Shuo Wu, Lijie Zhang, Ruidan Zhang, Kang Yang, Qin Wei, Qiyu Jia, Jian Guo, Chuang Ma   +7 more
doaj   +1 more source

Fibroblast Growth Factor-10 (FGF-10) Mobilizes Lung-resident Mesenchymal Stem Cells and Protects Against Acute Lung Injury. [PDF]

, 2016
FGF-10 can prevent or reduce lung specific inflammation due to traumatic or infectious lung injury. However, the exact mechanisms are poorly characterized.
Bai, Chunxue, Liu, Jie, Pan, Jue, Qu, Jieming, Rong, Linyi, Seeley, Eric J, Song, Yuanlin, Tang, Xinjun, Tong, Lin, Wang, Qin, Zhou, Jian, Zhu, Xiaodan   +11 more
core   +1 more source

Magnetic resonance imaging focused on the ferritin heavy chain 1 reporter gene detects neuronal differentiation in stem cells

Neural Regeneration Research, 2023
The neuronal differentiation of mesenchymal stem cells offers a new strategy for the treatment of neurological disorders. Thus, there is a need to identify a noninvasive and sensitive in vivo imaging approach for real-time monitoring of transplanted stem
Xiao-Ya He, Yi-Rui Zhou, Tong Mu, Yi-Fan Liao, Li Jiang, Yong Qin, Jin-Hua Cai   +6 more
doaj   +1 more source

Peran Bone Marrow Mesenchymal Stem Cells (BMMSC) dalam Perubahan Seluler Hyperplasia Kelenjar Adrenal Tikus Hipertensi [PDF]

, 2019
Dalam keadaan hipertensi, hyperplasia merupakan salah satu abnormalitas jaringan yang terlihat yang ditunjukkan dengan peningkatan jumlah sel dalam jaringan atau organ sehingga jaringan atau organ menjadi lebih besar ukurannya dari normal.
Nugroho, S. W. (Setyo), Rumlaklak, Y. Y. (Yanse), Sajuthi, D. (Dondin), Sulistiawati, E. (Erni), Widhyari, S. D. (Sus)   +4 more
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Profoundly reduced neovascularization capacity of bone marrow mononuclear cells derived from patients with chronic ischemic heart disease [PDF]

, 2004
Background— Cell therapy with bone marrow–derived stem/progenitor cells is a novel option for improving neovascularization and cardiac function in ischemic heart disease.
Aicher, A, Assmus, B, Dimmeler, S, Heeschen, C, Honold, J, Lehmann, R, Martin, H, Walter, DH, Zeiher, AM   +8 more
core   +1 more source