Results 21 to 30 of about 421,152 (353)

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation

open access: yesScientific Reports, 2020
Interleukin (IL)-6 is a pleiotropic cytokine involved in the regulation of hematological and immune responses. IL-6 is secreted chiefly by stromal cells, but little is known about its precise role in the homeostasis of human mesenchymal stromal cells ...
Akaitz Dorronsoro   +7 more
doaj   +1 more source

What is the impact of human umbilical cord mesenchymal stem cell transplantation on clinical treatment?

open access: yesStem cell research & therapeutics, 2020
Background Human umbilical cord mesenchymal stem cells (HUC-MSCs) present in the umbilical cord tissue are self-renewing and multipotent. They can renew themselves continuously and, under certain conditions, differentiate into one or more cell types ...
Qi Xie   +7 more
semanticscholar   +1 more source

Injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells promotes functional recovery in patients with spontaneous intracerebral hemorrhage: phase I clinical trial

open access: yesNeural Regeneration Research, 2023
Animal experiments have shown that injectable collagen scaffold with human umbilical cord-derived mesenchymal stem cells can promote recovery from spinal cord injury.
Xiao-Yin Li   +8 more
doaj   +1 more source

Photoreceptor protection by mesenchymal stem cell transplantation identifies exosomal MiR-21 as a therapeutic for retinal degeneration

open access: yesCell Death and Differentiation, 2020
Photoreceptor apoptosis is recognized as one key pathogenesis of retinal degeneration, the counteraction of which represents a promising approach to safeguard visual function.
Chun-Lei Deng   +10 more
semanticscholar   +1 more source

Therapeutic evidence of umbilical cord-derived mesenchymal stem cell transplantation for cerebral palsy: a randomized, controlled trial

open access: yesStem cell research & therapeutics, 2020
Cerebral palsy (CP) is a syndrome of childhood movement and posture disorders. Clinical evidence is still limited and sometimes inconclusive about the benefits of human umbilical cord mesenchymal stem cells (hUC-MSCs) for CP.
Jiaowei Gu   +13 more
semanticscholar   +1 more source

Mesenchymal Stem/Stromal Cells in Organ Transplantation

open access: yesPharmaceutics, 2022
Organ transplantation is essential and crucial for saving and enhancing the lives of individuals suffering from end-stage organ failure. Major challenges in the medical field include the shortage of organ donors, high rates of organ rejection, and long wait times.
Dayanand Deo   +2 more
openaire   +3 more sources

Understanding and leveraging cell metabolism to enhance mesenchymal stem cell transplantation survival in tissue engineering and regenerative medicine applications

open access: yesStem Cells, 2020
In tissue engineering and regenerative medicine, stem cell—specifically, mesenchymal stromal/stem cells (MSCs)—therapies have fallen short of their initial promise and hype.
G. E. Salazar-Noratto   +9 more
semanticscholar   +1 more source

Mesenchymal Stem Cells for Busulfan–Induced Azoospermia: An Experimental Study [PDF]

open access: yesInternational Journal of Medical Arts, 2022
Background: Busulfan is a frequently used chemotherapeutic agent. It exerts harmful effects on male reproduction. Azoospermia is a major cause of male infertility, and stem cell therapy may be a reasonable treatment option.The aim of the work:  The ...
Fawzy Mahmoud Ali Abougalala   +4 more
doaj   +1 more source

Co-transplantation of Human Fetal Mesenchymal and Hematopoietic Stem Cells in Type 1 Diabetic Mice Model

open access: yesFrontiers in Endocrinology, 2019
Introduction: Cell therapy can overcome the limitation of conventional treatments (including different medications and β cell replacement) for type 1 diabetes.
Babak Arjmand   +8 more
doaj   +1 more source

Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts [PDF]

open access: yes, 2010
Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner   +5 more
core   +1 more source

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