Results 31 to 40 of about 5,762,651 (303)
Mesenchymal stem cells for inducing tolerance in organ transplantation [PDF]
Organ transplantation is useful for treating the end stage of organ failure. The induction of tolerance to the transplanted organ is essential for its long-term survival. Immunologic tolerance can be induced by immunosuppressive agents and mixed chimerism.
Guo, Kequan, Ikehara, Susumu, Meng, Xu
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BackgroundKeratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries ...
Hongshan Liu +7 more
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Mesenchymal Stem Cells for the Treatment of Liver Disease: Present and Perspectives
Mesenchymal stem cell transplantation is an emerging therapy for treating chronic liver diseases. The potential of this treatment has been evaluated in preclinical and clinical studies. Although the mechanisms of mesenchymal stem cell transplantation are
Seong Hee Kang +3 more
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Although there have been reports of promising results regarding the transplantation of mesenchymal stem cells (MSCs) for neurodegenerative diseases through the use of neuronal differentiation or control of the microenvironment, traditional surgical ...
Jihyeon Lee +8 more
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Transplantation of mesenchymal stem cells in ALS
Amyotrophic lateral sclerosis (ALS) is a devastating incurable, neurodegenerative disease that targets motor neurons (MNs) in the primary motor cortex, brainstem, and spinal cord, leading to muscle atrophy, paralysis, and death due to respiratory failure within 2-5 years. Currently, there is no cure for ALS.
Mazzini, Letizia +5 more
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Mesenchymal Stem Cells as Feeder Cells for Pancreatic Islet Transplants [PDF]
Allogeneic islet transplantation serves as a source of insulin-secreting beta-cells for the maintenance of normal glucose levels and treatment of diabetes. However, limited availability of islets, high rates of islet graft failure, and the need for life-long non-specific immunosuppressive therapy are major obstacles to the widespread application of ...
Sordi V., Piemonti L.
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Encapsulation of Mesenchymal Stem Cells: Dissecting the Underlying Mechanism of Mesenchymal Stem Cell Transplantation Therapy [PDF]
Mesenchymal stem cells (MSCs) are widely considered good candidates for cell transplantation therapy. Various central nervous system disorders have been suggested as suitable targets for MSC transplantation therapy. In this context, a great deal of basic and clinical research has been conducted to explore its clinical uses.
Kyohei Kin, Takao Yasuhara, Isao Date
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Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]
INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie +24 more
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Mesenchymal Stem Cells and Clinical Application in Chronic Lung Diseases
Mesenchymal stem cells are a multipotent mature non hematopoietic stem cells, with characteristics such as ability to self-renew and differentiate in mesodermal, ectodermal, and endodermal pathway.
Isti Mardiana Soetartio, Triya Damayanti
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Mesenchymal stem cell transplantation in multiple sclerosis [PDF]
Mesenchymal stem cells (MSCs) are pluripotent non-hematopoietic precursor cells that can be isolated from bone marrow and numerous other tissues, culture-expanded to purity, and induced to differentiate in vitro and in vivo into mesodermal derivatives. MSCs exhibit many phenotypic and functional similarities to pericytes.
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