Results 31 to 40 of about 421,152 (353)

Noninvasive in vivo tracking of mesenchymal stem cells and evaluation of cell therapeutic effects in a murine model using a clinical 3.0 T MRI [PDF]

open access: yes, 2013
Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment approach for end-stage heart failure. However, little is known about the underlying mechanisms and the fate of the transplanted cells. The objective of the presented
Neef, Klaus   +11 more
core   +1 more source

Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies

open access: yesNeural Regeneration Research, 2016
Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood.
Guihong Li   +7 more
doaj   +1 more source

Mesenchymal Stem Cell Transplantation for Neurodegenerative Diseases

open access: yesCell Transplantation, 2008
Neurodegenerative diseases are characterized by a progressive degeneration of selective neural populations. The lack of effective treatment and the characteristic of their pathology make these diseases appropriate candidates for cell therapy. Mesenchymal stem cells (MSCs) are multipotent stem-like cells that are capable of differentiating into ...
Y. Torrente, E. Polli
openaire   +4 more sources

Hypoxic Culture Conditions as a Solution for Mesenchymal Stem Cell Based Regenerative Therapy [PDF]

open access: yes, 2014
Cell-based regenerative therapies, based on in vitro propagation of stem cells, offer tremendous hope to many individuals suffering from degenerative diseases that were previously deemed untreatable.
Haque, N.   +3 more
core   +1 more source

12 hours after cerebral ischemia is the optimal time for bone marrow mesenchymal stem cell transplantation

open access: yesNeural Regeneration Research, 2015
Cell therapy using stem cell transplantation against cerebral ischemia has been reported. However, it remains controversial regarding the optimal time for cell transplantation and the transplantation route.
Seyed Mojtaba Hosseini   +4 more
doaj   +1 more source

Mesenchymal stem cells in the treatment of ischemic stroke [PDF]

open access: yesКлиническая практика
Over the past two decades, multiple preclinical studies have shown that transplantation of mesenchymal stem cells leads to a pronounced positive effect in animals with experimental stroke.
Daria D. Namestnikova   +6 more
doaj   +1 more source

The potential use of mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]

open access: yesExperimental & Molecular Medicine, 2013
In the last 10 years, mesenchymal stem cells (MSCs) have emerged as a therapeutic approach to regenerative medicine, cancer, autoimmune diseases, and many more due to their potential to differentiate into various tissues, to repair damaged tissues and organs, and also for their immunomodulatory properties.
Kim, Eun-Jung   +2 more
openaire   +2 more sources

Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]

open access: yes, 2012
INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie   +24 more
core   +1 more source

Transplantation of mesenchymal stem cells to enhance engraftment of hematopoietic stem cells [PDF]

open access: yesLeukemia, 2007
Seven patients underwent treatment with mesenchymal stem cells (MSCs), together with allogeneic hematopoietic stem cell transplantation (HSCT). MSCs were given to three patients for graft failure and four patients were included in a pilot study. HSCT donors were three human leukocyte antigen (HLA)-identical siblings, three unrelated donors and one cord
K, Le Blanc   +9 more
openaire   +2 more sources

The role of mesenchymal stem cells in hematopoietic stem cell transplantation: prevention and treatment of graft-versus-host disease

open access: yesStem cell research & therapeutics, 2019
The use and effectiveness of hematopoietic stem cell transplantation (HSCT) are limited by lethal complications, i.e., acute and chronic graft-versus-host disease (aGVHD and cGVHD, respectively), in which immune cells from the donor attack healthy ...
Lu Zhao   +4 more
semanticscholar   +1 more source

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