Results 31 to 40 of about 5,762,651 (303)

Mesenchymal stem cells for inducing tolerance in organ transplantation [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2014
Organ transplantation is useful for treating the end stage of organ failure. The induction of tolerance to the transplanted organ is essential for its long-term survival. Immunologic tolerance can be induced by immunosuppressive agents and mixed chimerism.
Guo, Kequan, Ikehara, Susumu, Meng, Xu
openaire   +3 more sources

Cell therapy of congenital corneal diseases with umbilical mesenchymal stem cells: lumican null mice.

open access: yesPLoS ONE, 2010
BackgroundKeratoplasty is the most effective treatment for corneal blindness, but suboptimal medical conditions and lack of qualified medical personnel and donated cornea often prevent the performance of corneal transplantation in developing countries ...
Hongshan Liu   +7 more
doaj   +1 more source

Mesenchymal Stem Cells for the Treatment of Liver Disease: Present and Perspectives

open access: yesGut and Liver, 2020
Mesenchymal stem cell transplantation is an emerging therapy for treating chronic liver diseases. The potential of this treatment has been evaluated in preclinical and clinical studies. Although the mechanisms of mesenchymal stem cell transplantation are
Seong Hee Kang   +3 more
doaj   +1 more source

Non-invasively enhanced intracranial transplantation of mesenchymal stem cells using focused ultrasound mediated by overexpression of cell-adhesion molecules

open access: yesStem Cell Research, 2020
Although there have been reports of promising results regarding the transplantation of mesenchymal stem cells (MSCs) for neurodegenerative diseases through the use of neuronal differentiation or control of the microenvironment, traditional surgical ...
Jihyeon Lee   +8 more
doaj   +1 more source

Transplantation of mesenchymal stem cells in ALS

open access: yes, 2012
Amyotrophic lateral sclerosis (ALS) is a devastating incurable, neurodegenerative disease that targets motor neurons (MNs) in the primary motor cortex, brainstem, and spinal cord, leading to muscle atrophy, paralysis, and death due to respiratory failure within 2-5 years. Currently, there is no cure for ALS.
Mazzini, Letizia   +5 more
openaire   +3 more sources

Mesenchymal Stem Cells as Feeder Cells for Pancreatic Islet Transplants [PDF]

open access: yesThe Review of Diabetic Studies, 2010
Allogeneic islet transplantation serves as a source of insulin-secreting beta-cells for the maintenance of normal glucose levels and treatment of diabetes. However, limited availability of islets, high rates of islet graft failure, and the need for life-long non-specific immunosuppressive therapy are major obstacles to the widespread application of ...
Sordi V., Piemonti L.
openaire   +2 more sources

Encapsulation of Mesenchymal Stem Cells: Dissecting the Underlying Mechanism of Mesenchymal Stem Cell Transplantation Therapy [PDF]

open access: yesNeuroscience Insights, 2020
Mesenchymal stem cells (MSCs) are widely considered good candidates for cell transplantation therapy. Various central nervous system disorders have been suggested as suitable targets for MSC transplantation therapy. In this context, a great deal of basic and clinical research has been conducted to explore its clinical uses.
Kyohei Kin, Takao Yasuhara, Isao Date
openaire   +3 more sources

Spatiotemporal evolution of early innate immune responses triggered by neural stem cell grafting [PDF]

open access: yes, 2012
INTRODUCTION: Transplantation of neural stem cells (NSCs) is increasingly suggested to become part of future therapeutic approaches to improve functional outcome of various central nervous system disorders. However, recently it has become clear that only
Van Der Linden, Anne-Marie   +24 more
core   +1 more source

Mesenchymal Stem Cells and Clinical Application in Chronic Lung Diseases

open access: yesJurnal Respirasi, 2021
Mesenchymal stem cells are a multipotent mature non hematopoietic stem cells, with characteristics such as ability to self-renew and differentiate in mesodermal, ectodermal, and endodermal pathway.
Isti Mardiana Soetartio, Triya Damayanti
doaj   +1 more source

Mesenchymal stem cell transplantation in multiple sclerosis [PDF]

open access: yesJournal of the Neurological Sciences, 2013
Mesenchymal stem cells (MSCs) are pluripotent non-hematopoietic precursor cells that can be isolated from bone marrow and numerous other tissues, culture-expanded to purity, and induced to differentiate in vitro and in vivo into mesodermal derivatives. MSCs exhibit many phenotypic and functional similarities to pericytes.
openaire   +2 more sources

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