Results 11 to 20 of about 5,762,651 (303)
Mesenchymal stem cell and hematopoietic stem cell transplantation for vasculitis
Vascular Investigation and Therapy, 2020 Vasculitis is a great therapeutic challenge. Currently, no effective treatments are available. Although biologics are emerging as new therapeutic alternatives, steroids remain the mainstay of the treatment.
Lianming Liao
doaj +3 more sources
Immunogenicity of allogeneic mouse mesenchymal stem cells (MSC) [PDF]
, 2012 Adult mesenchymal stem cells (MSC) are multipotential cells which can differentiate into various cell types thus giving them utility in tissue engineering regenerative medicine and cell-based therapies.
Mukonoweshuro, Blessing
core +6 more sources
Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]
Cytotherapy, 2009 Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo, Battiwalla, Peiman, Hematti
openaire +2 more sources
Mesenchymal stem cells and transplant tolerance [PDF]
Nephrology, 2014 AbstractDifferent strategies are being tried to induce transplant tolerance in clinical settings; however, none of them are both safe and effective. Mesenchymal stem cells have been found to be potent immunomodulators and immunosuppressants. We discuss in this review different sources of mesenchymal stem cells and the potent role of adipose tissue ...
Aruna V, Vanikar +4 more
openaire +2 more sources
Mesenchymal stem cells in transplantation and tissue regeneration [PDF]
Frontiers in Immunology, 2011 Mesenchymal stem cells (MSC) were identified in the 1960s as bone marrow cells capable of osteogenic differentiation (Friedenstein and Petrakova, 1966). In the following decennia, these cells were further attributed with the capacity to differentiate into adipogenic, chondrogenic, and myogenic lineages (Pittenger et al., 1999), to secrete trophic ...
Hoogduijn, Martin J., Dor, Frank J.
openaire +3 more sources
Mesenchymal Stem Cell Transplantation in Liver Diseases
Seminars in Liver Disease, 2022 Promising preclinical data suggested that bone marrow–derived mesenchymal stem cells (BM-MSC) can reduce hepatic fibrosis and stimulate liver regeneration. Preclinical studies moreover suggested that the immunomodulatory and anti-inflammatory functions of MSCs may reduce hepatic inflammation, improve liver function, and decrease infection incidences ...
Nevens, Frederik, van der Merwe, Schalk
openaire +2 more sources
Mesenchymal Stem/Stromal Cells in Organ Transplantation
Pharmaceutics, 2022 Organ transplantation is essential and crucial for saving and enhancing the lives of individuals suffering from end-stage organ failure. Major challenges in the medical field include the shortage of organ donors, high rates of organ rejection, and long wait times.
Dayanand Deo +2 more
openaire +3 more sources
Murine amniotic fluid stem cells contribute mesenchymal but not epithelial components to reconstituted mammary ducts [PDF]
, 2010 Introduction: Amniotic fluid harbors cells indicative of all three germ layers, and pluripotent fetal amniotic fluid stem cells (AFSs) are considered potentially valuable for applications in cellular therapy and tissue engineering.
Bernd Groner +5 more
core +1 more source
Neural Regeneration Research, 2016 Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood.
Guihong Li +7 more
doaj +1 more source
Noninvasive in vivo tracking of mesenchymal stem cells and evaluation of cell therapeutic effects in a murine model using a clinical 3.0 T MRI [PDF]
, 2013 Cardiac cell therapy with mesenchymal stem cells (MSCs) represents a promising treatment approach for end-stage heart failure. However, little is known about the underlying mechanisms and the fate of the transplanted cells. The objective of the presented
Neef, Klaus +11 more
core +1 more source