Results 11 to 20 of about 421,152 (353)

Potential mechanisms and therapeutic targets of mesenchymal stem cell transplantation for ischemic stroke

open access: yesStem cell research & therapeutics, 2022
Ischemic stroke is one of the major causes of death and disability in the world. Currently, most patients cannot choose intravenous thrombolysis or intravascular mechanical thrombectomy because of narrow therapeutic windows and severe complications. Stem
Li Zhou   +12 more
semanticscholar   +1 more source

Mesenchymal Stem Cell Transplantation Increases Antioxidant Protein Expression and Ameliorates GP91/ROS/Inflammasome Signals in Diabetic Cardiomyopathy

open access: yesJournal of Cardiovascular Development and Disease, 2022
Background: Cardiomyopathy is one of the complications associated with diabetes. Due to its high prevalence, diabetic cardiomyopathy has become an urgent issue for diabetic patients.
Wei-Syun Hu   +4 more
doaj   +1 more source

Effects of bone marrow mesenchymal stem cell transplantation on tumor necrosis factor-alpha receptor 1 expression, granulosa cell apoptosis, and folliculogenesis repair in endometriosis mouse models [PDF]

open access: yesVeterinary World, 2021
Background and Aim: Endometriosis affects the ovaries and causes a decrease in the oocyte quality during endometrial receptivity. During the development of ovarian follicles, paracrine communication occurs between granulosa cells and oocytes.
Sri Ratna Dwiningsih   +7 more
doaj   +1 more source

Mesenchymal stem cells in hematopoietic stem cell transplantation [PDF]

open access: yesCytotherapy, 2009
Mesenchymal stromal/stem cells (MSC) of bone marrow (BM) origin not only provide the supportive microenvironmental niche for hematopoietic stem cells (HSC) but are capable of differentiating into various cell types of mesenchymal origin, such as bone, fat and cartilage.
Minoo, Battiwalla, Peiman, Hematti
openaire   +2 more sources

Mesenchymal stem cells and transplant tolerance [PDF]

open access: yesNephrology, 2014
AbstractDifferent strategies are being tried to induce transplant tolerance in clinical settings; however, none of them are both safe and effective. Mesenchymal stem cells have been found to be potent immunomodulators and immunosuppressants. We discuss in this review different sources of mesenchymal stem cells and the potent role of adipose tissue ...
Aruna V, Vanikar   +4 more
openaire   +2 more sources

Mesenchymal stem cells in transplantation and tissue regeneration [PDF]

open access: yesFrontiers in Immunology, 2011
Mesenchymal stem cells (MSC) were identified in the 1960s as bone marrow cells capable of osteogenic differentiation (Friedenstein and Petrakova, 1966). In the following decennia, these cells were further attributed with the capacity to differentiate into adipogenic, chondrogenic, and myogenic lineages (Pittenger et al., 1999), to secrete trophic ...
Hoogduijn, Martin J., Dor, Frank J.
openaire   +3 more sources

Bone marrow mesenchymal stem cells and exercise restore motor function following spinal cord injury by activating PI3K/AKT/mTOR pathway

open access: yesNeural Regeneration Research, 2023
Although many therapeutic interventions have shown promise in treating spinal cord injury, focusing on a single aspect of repair cannot achieve successful and functional regeneration in patients following spinal cord injury .
Xin Sun   +10 more
doaj   +1 more source

Advances in mesenchymal stem cell transplantation for the treatment of osteoporosis

open access: yesCell Proliferation, 2020
Osteoporosis is a systemic metabolic bone disease with characteristics of bone loss and microstructural degeneration. The personal and societal costs of osteoporosis are increasing year by year as the ageing of population, posing challenges to public ...
Yu-hua Jiang   +4 more
semanticscholar   +1 more source

Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis.

open access: yesBrain : a journal of neurology, 2020
In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) transplantation in patients with active and progressive multiple sclerosis. Forty-
P. Petrou   +14 more
semanticscholar   +1 more source

Mesenchymal Stem Cell in Pancreatic Islet Transplantation

open access: yesBiomedicines, 2023
Pancreatic islet transplantation is a therapeutic option for achieving physiologic regulation of plasma glucose in Type 1 diabetic patients. At the same time, mesenchymal stem cells (MSCs) have demonstrated their potential in controlling graft rejection, the most fearsome complication in organ/tissue transplantation.
Serena Barachini   +6 more
openaire   +4 more sources

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