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Archives of Medical Research, 2003
It has become clear that adult mammalian bone marrow contains not one but two ostensibly discrete populations of adult stem cells. The first and by far the most fully characterized are the hematopoietic stem cells responsible for maintaining lifelong production of blood cells.
Brenton Short +4 more
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It has become clear that adult mammalian bone marrow contains not one but two ostensibly discrete populations of adult stem cells. The first and by far the most fully characterized are the hematopoietic stem cells responsible for maintaining lifelong production of blood cells.
Brenton Short +4 more
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Journal of Orthopaedic Research, 1991
AbstractBone and cartilage formation in the embryo and repair and turnover in the adult involve the progeny of a small number of cells called mesenchymal stem cells. These cells divide, and their progeny become committed to a specific and distinctive phenotypic pathway, a lineage with discrete steps and, finally, end‐stage cells involved with ...
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AbstractBone and cartilage formation in the embryo and repair and turnover in the adult involve the progeny of a small number of cells called mesenchymal stem cells. These cells divide, and their progeny become committed to a specific and distinctive phenotypic pathway, a lineage with discrete steps and, finally, end‐stage cells involved with ...
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Annual Review of Cell and Developmental Biology, 2014
Two opposing descriptions of so-called mesenchymal stem cells (MSCs) exist at this time. One sees MSCs as the postnatal, self-renewing, and multipotent stem cells for the skeleton. This cell coincides with a specific type of bone marrow perivascular cell.
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Two opposing descriptions of so-called mesenchymal stem cells (MSCs) exist at this time. One sees MSCs as the postnatal, self-renewing, and multipotent stem cells for the skeleton. This cell coincides with a specific type of bone marrow perivascular cell.
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MicroRNAs and Mesenchymal Stem Cells
2011In the adult body, mesenchymal stem cells (MSCs) represent a population with self-renewal ability and multipotent differentiation capabilities. The phenotype of these cells is modulated by a dynamic interplay of signals within a defined microenvironment.
Collino F. +4 more
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Mesenchymal Stem Cell Mechanobiology
Current Osteoporosis Reports, 2010Bone marrow-derived multipotent stem and stromal cells (MSCs) are likely candidates for cell-based therapies for various conditions including skeletal disease. Advancement of these therapies will rely on an ability to identify, isolate, manipulate, and deliver stem cells in a safe and effective manner.
Christopher R. Jacobs +1 more
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Mesenchymal stem cells in immunoregulation [PDF]
Immunology & Cell Biology, 2006 Mesenchymal stem cells are present within the bone marrow cavity and serve as a reservoir for the continuous renewal of various mesenchymal tissues. Recent studies suggest that mesenchymal stem cells modulate immune reactions in vitro and escape from immune surveillance in vivo.
Armstrong, Marilyn, Chen, X., Li, Gang
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2020
This chapter focuses on mesenchymal stem cells (MSCs), a multipotent stem cell type that has been found in a variety of tissues and organs of the human body since their discovery in 1970. Their main function is to maintain and repair the respective tissue in vivo.
Margit Schulze +3 more
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This chapter focuses on mesenchymal stem cells (MSCs), a multipotent stem cell type that has been found in a variety of tissues and organs of the human body since their discovery in 1970. Their main function is to maintain and repair the respective tissue in vivo.
Margit Schulze +3 more
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Mesenchymal Stem Cell Engineering
2018Mesenchymal stem cells (MSC) are multipotent stem cells that display the capacity to generate the tissue in which they reside. MSC have been used as progenitor cells to engineer cartilage implants that can be used to repair chondral and osteochondral lesions, or as trophic producers of bioactive factors to initiate endogenous regenerative activities in
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Proteome of mesenchymal stem cells
PROTEOMICS, 2007AbstractProteomics has evolved, in recent years, into effective tools for basic and applied stem cell research, and has been extensively used to facilitate the identification of changes in signal transduction components, especially with regard to plasticity, proliferation, and differentiation.
Jun Seop Shin +2 more
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Mesenchymal Autologous Stem Cells
World Neurosurgery, 2015The use of cell-based therapies for spinal cord injuries has recently gained prominence as a potential therapy or component of a combination strategy. Experimental and clinical studies have been performed using mesenchymal stem cell therapy to treat spinal cord injuries with encouraging results.
Jaderson Costa da Costa +1 more
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