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MicroRNAs and Mesenchymal Stem Cells
2011In the adult body, mesenchymal stem cells (MSCs) represent a population with self-renewal ability and multipotent differentiation capabilities. The phenotype of these cells is modulated by a dynamic interplay of signals within a defined microenvironment.
Federica, Collino +4 more
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Mesenchymal stem cells in osteoarthritis
Current Opinion in Rheumatology, 2004Accumulating evidence indicates that every tissue contains stem cells. Our understanding of the biology of stem cells reveals that these cell populations have a critical role in the homeostasis and repair of tissues. Besides the local stem cell niches, additional compartments in the body such as the bone marrow may serve as reservoirs for stem cell ...
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Mesenchymal Stem/Stromal Cells: MESENCHYMAL STEM/STROMAL CELLS
Cytotherapy, 2023E. Heyman +3 more
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Mesenchymal stem cells and haematopoietic stem cell transplantation
Best Practice & Research Clinical Haematology, 2004The bone marrow serves as a reservoir for different classes of stem cells. In addition to haemopoietic stem cells, the bone marrow comprises a population of marrow stromal cells or mesenchymal stem cells (MSCs). These cells exhibit multilineage differentiation capacity, and are able to generate progenitors with restricted developmental potential ...
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Mesenchymal Stem Cells and Haematopoietic Stem Cell Culture
2012Haematopoietic stem cell (HSC) transplantation is an established cell-based therapy for a number of haematological malignancies and immunodeficiency diseases. However, the limited number of HSC from umbilical cord blood (UCB) limits the efficacy of transplants from this source.
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