Results 121 to 130 of about 90,342 (257)

Dual‐Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic Collagen Membrane for Cartilage Repair

open access: yesArthroscopy Techniques, EarlyView.
Abstract Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix‐induced chondrogenesis plus procedure for full‐thickness knee cartilage lesions uses a collagen matrix combined with shaver‐minced cartilage graft and bone ...
Leonardo Ataíde   +5 more
wiley   +1 more source

Single-cell transcriptome analysis of stem cells from human exfoliated deciduous teeth investigating functional heterogeneity in immunomodulation

open access: yesScientific Reports
Mesenchymal stem cells (MSCs) have been widely used in the treatment of various inflammatory diseases. The inadequate understanding of MSCs and their heterogeneity can impact the immune environment, which may be the cause of the good outcomes of MSCs ...
Yin Li   +7 more
doaj   +1 more source

Regenerative Potential of Mesenchymal Stem Cells' (MSCs) Secretome for Liver Fibrosis Therapies. [PDF]

open access: yesInt J Mol Sci, 2021
Nazarie Ignat SR   +4 more
europepmc   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner   +7 more
wiley   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

Corrigendum to "Sox9 augments BMP2-induced chondrogenic differentiation by downregulating Smad7 in mesenchymal stem cells (MSCs)" [Genes & Diseases 4 (2017) 229-239]. [PDF]

open access: yesGenes Dis, 2023
Zhao C   +17 more
europepmc   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

open access: yesBMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong   +11 more
wiley   +1 more source

Tetraspanin‐ESCRT sorting drives miR‐29b packaging into extracellular vesicles to reverse fibrosis in intrauterine adhesions

open access: yesBMEMat, EarlyView.
MiR‐29b is enriched in extracellular vesicles (EVs) via a tetraspanin transporter‐dependent endocytosis and sorting complex required for the endosomal transport (ESCRT)‐dependent pathway. These EVs target the 3′ untranslated region (3′UTR) of TGFB2, thereby inhibiting the TGF‐β/Smad3 signaling pathway and repairing endometrial damage in intrauterine ...
Lihao Chen   +10 more
wiley   +1 more source

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