Results 221 to 230 of about 90,342 (257)

Soluble Epoxide Hydrolase Inhibition Regulates Septoclast Activity to Promote Long Bone Growth and Fracture Healing by Enhancing Endothelial‐to‐Mesenchymal Notch Signalling

Cell Proliferation, EarlyView.
The sEH inhibitor TPPU upregulates endothelial HIF‐1α, activating the NOTCH signalling pathway between endothelial cells and mesenchymal stem cells. This promotes the differentiation and formation of FABP5+ septoclasts, enhances their participation in endochondral ossification, and ultimately improves longitudinal bone growth and fracture healing ...
Weixian Chen, Liangliang Liu, Xumeng Wang, Juanjuan Li, Jingyi Zhang, Xiaoli Shi, Qing Sun, Xu Chang, Jing Zhang, Jie Zhao, Fu Wang   +10 more
wiley   +1 more source

Ultrastructural Characteristics of Sheep and Horse Mesenchymal Stem Cells (MSCs)

Microscopy Research, 2013
In the present study, the morphological and ultrastructural characteristics of mesenchymal stem cells (MSCs) induced towards osteogenic, adipogenic, and chondrogenic lineages were investigated. The main objective of this paper was to focus on the differentiation capacity of ovine [oMSCs] and equine MSCs [eMSCs]. Bone marrow [BM] MSCs were isolated from
Irem Gul Sancak
exaly   +4 more sources

Research progress on Mesenchymal Stem Cells (MSCs), Adipose-Derived Mesenchymal Stem Cells (AD-MSCs), Drugs, and Vaccines in Inhibiting COVID-19 Disease

Aging and disease, 2020
Mesenchymal Stem Cells (MSCs), and Adipose-Derived Mesenchymal Stem Cells (AD-MSCs) have been used for many years in regenerative medicine for clinical and surgical applications. Additionally, recent studies reported improved respiratory activity after intravenous administration of MSCs into patients affected by coronavirus disease 2019 (COVID-19 ...
Simone Garcovich, Aris Sterodimas, Pietro Gentile   +2 more
exaly   +4 more sources

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Cell and gene therapy using mesenchymal stem cells (MSCs)

Journal of Autoimmunity, 2008
Mesenchymal stem cells (MSCs) are considered to be a promising platform for cell and gene therapy for a variety of diseases. First, in the field of hematopoietic stem cell transplantation, there are two applications of MSCs: 1) the improvement of stem cell engrafting and the acceleration of hematopoietic reconstitution based on the hematopoiesis ...
Keiya, Ozawa, Kazuya, Sato, Iekuni, Oh, Katsutoshi, Ozaki, Ryosuke, Uchibori, Yoko, Obara, Yuji, Kikuchi, Takayuki, Ito, Takashi, Okada, Masashi, Urabe, Hiroaki, Mizukami, Akihiro, Kume   +11 more
openaire   +2 more sources

Mesenchymal Stem Cells/Multipotent Mesenchymal Stromal Cells (MSCs)

The International Journal of Lower Extremity Wounds, 2012
Chronic wounds remain a major challenge in modern medicine and represent a significant health care burden. Several treatments have been suggested, but without a full understanding of the exact mechanism by which chronic wound occurs. Numerous studies have shown that mesenchymal stem cells/multipotent mesenchymal stromal cells (MSCs) may have ...
Ji-Ping, Zou, Sha, Huang, Yan, Peng, Hong-Wei, Liu, Biao, Cheng, Xiao-Bing, Fu, Xiao-Fei, Xiang   +6 more
openaire   +2 more sources

Regenerative Capacity of Adipose Derived Stem Cells (ADSCs), Comparison with Mesenchymal Stem Cells (MSCs) [PDF]

International Journal of Molecular Sciences, 2019
Adipose tissue is now on the top one of stem cell sources regarding its accessibility, abundance, and less painful collection procedure when compared to other sources. The adipose derived stem cells (ADSCs) that it contains can be maintained and expanded in culture for long periods of time without losing their differentiation capacity, leading to large
Loubna Mazini, Mazini Loubna, Rochette Luc   +2 more
exaly   +3 more sources

Development and evaluation of IL‐6 overexpressing mesenchymal stem cells (MSCs)

Journal of Tissue Engineering and Regenerative Medicine, 2021
Mesenchymal stem/stromal cell (MSC) therapy has been investigated in multiple diseases and conditions. Although the mechanisms of MSC-based therapies are not fully understood, we and others have shown interleukin 6 (IL-6) to be an important factor in MSC function.
Peng Huang, Cuiping Zhang, Mina Delawary, Jennifer A. Korchak, Koji Suda, Abba C. Zubair   +5 more
openaire   +2 more sources

Mesenchymal Stem Cells (MSCs) Therapy for Recovery of Fertility: a Systematic Review

Stem Cell Reviews and Reports, 2017
In recent years, the mesenchymal stem cells (MSCs) have provided the new opportunities to treat different disorders including infertility. Different studies have suggested that the MSCs have ability to differentiate into germ-like cells under specific induction conditions as well as transplantation to gonadal tissues.
Mir Davood Omrani, Sayyed Mohammad Hossein Ghaderian, Zahra Fazeli   +2 more
exaly   +3 more sources

Role of MicroRNA 21 in Mesenchymal Stem Cell (MSC) Differentiation: A Powerful Biomarker in MSCs Derived Cells

Current Pharmaceutical Biotechnology, 2015
The significant role of microRNAs (miRNAs) in stem cell development has been expansively discussed in recent publications and they are noticed to be involved in post transcriptional regulation of gene expression by its affinity towards the 3'UTR of target mRNA.
Durairaj, Sekar, Subramanian, Saravanan, Kulandaivelu, Karikalan, Krishnaraj, Thirugnanasambantham, Perumal, Lalitha, Villianur I H, Islam   +5 more
openaire   +2 more sources