Results 121 to 130 of about 138,445 (169)

Mesenchymal Stromal Cell Cryopreservation

Biopreservation and Biobanking, 2012
The advent of stem cells and stem cell-based therapies for specific diseases requires particular knowledge of laboratory procedures, which not only guarantee the continuous production of cells, but also provide them an identity and integrity as close as possible to their origin.
Sabrina, Renzi, Tina, Lombardo, Silvia, Dotti, Sara S, Dessì, Pasquale, De Blasio, Maura, Ferrari   +5 more
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Stromal Mesenchymal Progenitor Cells

Leukemia & Lymphoma, 1999
The precursors of bone, cartilage, fat and muscle cells are likely to be derived from more primitive mesenchymal cells which exhibit some of the characteristics of stem cells. Despite extensive study of stromal cell differentiation, neither mesenchymal stem cells or the more committed, tissue-specific progenitors have been well characterized.
R, Ghilzon, C A, McCulloch, R, Zohar
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Reinventing mesenchymal stromal cells

Cytotherapy, 2012
The life-saving impact of chemotherapy and radiation has been as remarkable and momentous as any advance in the history of medicine. This becomes even more signifi cant when we remind ourselves that 50 years ago nearly all leukemias, lymphomas and aggressive solid tumors were fatal, and that nearly everything in oncology before the 20th century was a ...
Jakub, Tolar, Miroslav, Tolar
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Immunogenicity of mesenchymal stromal/stem cells

Scandinavian Journal of Immunology, 2023
AbstractMesenchymal stromal/stem cells (MSCs) possess the ability to self‐renew and differentiate into other cell types. Because of their anti‐inflammatory and immunomodulatory abilities, as well as their more ready availability compared to other stem cell sources, MSCs hold great promise for the treatment of many diseases, such as haematological ...
Wenyan Chen, Lu Lv, Na Chen, Enhai Cui
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Multipotent mesenchymal stromal cells in otorhinolaryngology

Medical Hypotheses, 2014
Multipotent mesenchymal stromal cells (MSCs) are primitive cells capable of restoring damaged mesenchyme and with the ability to differentiate into mature cells of bone, cartilage, muscle, fat, nerve or fibrous tissues. MSCs are therefore good candidates for applications in regenerative medicine and cell based therapy.
Lukas, Skoloudik, Viktor, Chrobok, David, Kalfert, Zuzana, Koci, Stanislav, Filip   +4 more
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Challenges for mesenchymal stromal cell therapies

Science Translational Medicine, 2019
Clinical trials of mesenchymal stromal cell therapies reveal a challenging heterogeneous landscape, including diverse therapeutic targets, patient categories, cell sources, and potential mechanisms of action.
Ivan Martin, Jacques Galipeau, Charles Kessler, Katarina Le Blanc, Francesco Dazzi   +4 more
openaire   +3 more sources

Mesenchymal stromal cells for sphincter regeneration

Advanced Drug Delivery Reviews, 2015
Stress urinary incontinence (SUI), defined as the involuntary loss of considerable amounts of urine during increased abdominal pressure (exertion, effort, sneezing, coughing, etc.), is a severe problem to the individuals affected and a significant medical, social and economic challenge.
Klein, Gerd, Hart, Melanie L., Brinchmann, Jan E., Rolauffs, Bernd, Stenzl, Arnulf, Sievert, Karl-Dietrich, Aicher, Wilhelm K.   +6 more
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Homing properties of mesenchymal stromal cells

Expert Opinion on Biological Therapy, 2014
A large number of clinical trials are underway to assess the therapeutic potential of mesenchymal stromal cells. This is based on preclinical observations that point to the probable efficacy of these cells. Very little is known however about the homing mechanisms of these cells to sites of injury and inflammation. This is important if one is to enhance
Kallmeyer, Karlien, Pepper, Michael Sean
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Mesenchymal stromal cells.

Annals of the New York Academy of Sciences, 2009
Mesenchymal stromal cells (MSCs) are multipotent cells that can be isolated from several human tissues and expanded ex vivo for clinical use. MSCs are identified by their adherent properties, immunephenotype, and differentiation potential. MSCs display immunological properties that have been demonstrated both in vitro and in vivo, in animal models and ...
Maria Ester, Bernardo, Franco, Locatelli, Willem E, Fibbe   +2 more
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Heterogeneity of mesenchymal stromal cell preparations

Cytotherapy, 2008
As an archetype of human adult stem cells that can readily be harvested, enriched and expanded in vitro, mesenchymal stromal cells (MSC) have been reported to be of significance for regenerative medicine. The literature is replete with reports on their developmental potentials in pre-clinical model systems.
A D, Ho, W, Wagner, W, Franke
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