Results 31 to 40 of about 43,063 (305)
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Design and finite element mode analysis of noncircular gear [PDF]
, 2008 The noncircular gear transmission is an important branch of the gear transmission, it is characterized by its compact structure, good dynamic equilibration and other advantages, and can be used in the automobile, engineering machine, ship, machine tool ...
Cheng, K +5 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Gear wear process monitoring using acoustic signals [PDF]
, 2014 Airborne acoustic signals contain valuable information from machines and can be detected remotely for condition monitoring. However, the signal is often seriously contaminated by various noises from the environment as well as nearby machines.
Ahmaida, Anwar +3 more
core
A novel approach to modelling and simulating the contact behaviour between a human hand model and a deformable object [PDF]
, 2012 A deeper understanding of biomechanical behaviour of human hands becomes fundamental for any human hand-operated Q2 activities. The integration of biomechanical knowledge of human hands into product design process starts to play an increasingly important
Chamoret, D +5 more
core +4 more sources
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Identifying combinations of tetrahedra into hexahedra: a vertex based strategy
, 2018 Indirect hex-dominant meshing methods rely on the detection of adjacent tetrahedra an algorithm that performs this identification and builds the set of all possible combinations of tetrahedral elements of an input mesh T into hexahedra, prisms, or ...
Johnen, Amaury +3 more
core +1 more source
Jixie chuandong, 2017 The radial deformation is one of the important parameters that affect meshing characteristic and the life of flexspline in harmonic reducer. Based on envelope meshing theory of harmonic drive,the influence of radial deformation on meshing characteristic ...
Zhang Liyong +5 more
doaj
Journal of Mechanical Engineering, 2023 Based on the results obtained in the previous research, the values of meshing characteristics of profile shifted quasi-involute arc-tooth-trace gears is calculated.
Tkach Pavlo +5 more
doaj +1 more source