Results 31 to 40 of about 1,188,283 (296)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Jixie chuandong, 2017 The radial deformation is one of the important parameters that affect meshing characteristic and the life of flexspline in harmonic reducer. Based on envelope meshing theory of harmonic drive,the influence of radial deformation on meshing characteristic ...
Zhang Liyong +5 more
doaj
Journal of Mechanical Engineering, 2023 Based on the results obtained in the previous research, the values of meshing characteristics of profile shifted quasi-involute arc-tooth-trace gears is calculated.
Tkach Pavlo +5 more
doaj +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Radial Inflow Turbine Meshing Rev. 1
, 2015 This report describes meshing utilities to support the mesh generation for Radial Inflow Turbines. This includes two tools: (a) parameterised mesh generator for Nozzle Guide Vanes; (b) a geometry and mesh generation tool for turbine rotors. A key feature
Jahn, Ingo
core +1 more source
Jixie chuandong, 2012 According to characteristic of point-line meshing gear and basic law of meshing,a common no meshing backlash equation of point-line meshing gear,a calculation formula about least modification coefficient of straight tooth point-line meshing gear and ...
丁军, 黄海, 厉海祥, 周晓菊
doaj
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
, 2023 (a) Overall meshing, (b) Local meshing of the front axle, (c) Local meshing of the rear axle.
Liang Cheng (228343) +2 more
core +1 more source
Combined Adaptive Meshing Technique and a Characteristic-based Finite Volume Element Method for Solving Convection-Diffusion-Reaction Equation [PDF]
, 2013 A finite volume element method is combined with an adaptive meshing technique to solve the two-dimensional unsteady convection-diffusion-reaction equation.
Theeraek, P.
core +2 more sources