Results 11 to 20 of about 4,748 (264)

MESHING THEORY ANALYSIS OF THE MODIFIED ROLLER ENVELOPING HOURGLASS WORM DRIVE

open access: yesJixie qiangdu, 2022
Based on the modification of the single-roller-enveloped toroidal meshing worm drive, a parabolic modified roller-enveloped toroidal meshing worm drive is obtained.
QI Yan   +4 more
doaj  

Meshing theory of axial arc tooth profile cylindrical worm drive

open access: yesAdvances in Mechanical Engineering, 2021
In this paper, the axial arc tooth profile cylindrical worm drive is proposed, whose worm is cut by turning tool. Due to the simple processing equipment, short manufacturing time and low cost, this kind of worm can replace the cylindrical worm ground by ...
Yunuo Liu   +3 more
doaj   +1 more source

Influence of rotational speed and torque on meshing efficiency of double helical gear transmission system

open access: yesMechanics & Industry, 2021
The accuracy of gear meshing efficiency model is the key to study the influence factors of gear meshing efficiency. Experiment is an effective method to verify the theory model.
Wang Cheng
doaj   +1 more source

General theory of interpolation error estimates on anisotropic meshes [PDF]

open access: yesJapan Journal of Industrial and Applied Mathematics, 2020
We propose a general theory of estimating interpolation error for smooth functions in two and three dimensions. In our theory, the error of interpolation is bound in terms of the diameter of a simplex and a geometric parameter. In the two-dimensional case, our geometric parameter is equivalent to the circumradius of a triangle. In the three-dimensional
Hiroki Ishizaka   +2 more
openaire   +2 more sources

A continuum theory for unstructured mesh generation in two dimensions [PDF]

open access: yesComputer Aided Geometric Design, 2008
A continuum description of unstructured meshes in two dimensions, both for planar and curved surface domains, is proposed. The meshes described are those which, in the limit of an increasingly finer mesh (smaller cells), and away from irregular vertices, have ideally-shaped cells (squares or equilateral triangles), and can therefore be completely ...
openaire   +3 more sources

Antiskid Design Method and Simulation Optimization of Rope Rail Conveyors

open access: yesJixie chuandong, 2023
The rope rail conveyor has certain advantages over the belt conveyor in long-distance transportation, but the antiskid problem of its driving system has not been paid attention to.
Zhao Huijian   +4 more
doaj  

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Theory of hydrodynamic phenomena in optical mesh lattices

open access: yesPhysical Review A, 2023
Signatures of superfluid-like behaviour have recently been observed experimentally in a nonlinear optical mesh lattice, where the arrival time of optical pulses propagating in a pair of coupled optical fiber loops is interpreted as a synthetic spatial dimension. Here, we develop a general theory of the fluid of light in such optical mesh lattices.
Hannah M. Price   +4 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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