Results 41 to 50 of about 5,399,073 (248)

Generation principle and meshing characteristics of conjugate-curve circular arc gears

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing, 2015
The generation principle and meshing characteristics of conjugate-curve circular arc gears, which is proposed based on the theory of conjugate curves, are studied in this paper.
Dong LIANG   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

渐开线斜齿圆柱齿轮齿面接触强度分析

open access: yesJixie chuandong, 2014
The total contact line length isn’t a constant value during a meshing period of helical gear pair. However the length will have an affect on the linear load which acts on helical gear pair,so the variational law of contact line length during a meshing ...
李宁, 李威
doaj  

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Finite element modelling and load share analysis for involute worm gears with localised tooth contact [PDF]

open access: yes, 2001
A new approach has been developed by the authors to estimate the load share of worm gear drives, and to calculate the instantaneous tooth meshing stiffness and loaded transmission errors. In the approach, the finite element (FE) modelling is based on the
Gentle, CR, Su, D, Yang, F
core  

MESHING PERFORMANCE ANALYSIS OF TAPERED ROLLER ENVELOPING END FACE MESHING WORM DRIVE (MT)

open access: yes, 2023
The end face meshing worm drive with tapered roller envelope has many simultaneous meshing tooth pairs and can eliminate clearance. According to the gear meshing principle and differential geometry principle, the meshing mathematical model of the ...
LIAO HongHui   +3 more
core   +1 more source

Research on the forming theory analysis and digital model of circular arc gear

open access: yes工程科学与技术, 2016
:To study the forming principle of circular arc gear shaped by rotary cutter ,get a reliable circular arc gear 3D model to guide the manufacturing processing and simulation calculation, according to the development of the cutter and the gear workpiece ...
zhaofei, duanyang
doaj  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

A mesh‐in‐element method for the theory of porous media

open access: yesInternational Journal for Numerical Methods in Engineering
AbstractWhile direct homogenisation approaches such as the FE method are subject to the assumption of scale separation, the mesh‐in‐element (MIEL) approach is based on an approach with strong scale coupling, which is based on a discretization with finite elements. In this contribution we propose a two‐scale MIEL scheme in the framework of the theory of
S. Maike   +3 more
openaire   +4 more sources

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

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