Results 51 to 60 of about 5,399,073 (248)

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

open access: yesFEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard   +12 more
wiley   +1 more source

Quality assessment of Smooth Block-Unstructured Mixed Meshes for Aerodynamic Applications [PDF]

open access: yes, 2012
Generating smooth mixed block-unstructured meshes is a promising way to reduce mesh sizes for outer aerodynamic flow analysis. Beyond the core part of the mesh generation, the smooth meshing of the boundary layer region by structured hexahedrons and ...
Wild, Jochen
core  

A Novel Method for the Fault Diagnosis of a Planetary Gearbox based on Residual Sidebands from Modulation Signal Bispectrum Analysis [PDF]

open access: yes, 2014
This paper presents a novel method for the fault diagnosis of planetary gearboxes based on an accurate estimation of residual sidebands using a modulation signal bispectrum (MSB).
Gu, Fengshou   +4 more
core   +3 more sources

Research on Curvature Interference Characteristics of Conical Surface Enveloping Cylindrical Worm–Face Worm Gear Drive

open access: yesApplied Sciences
This study proposes the use of Physics-Informed Neural Networks (PINNs) to further advance the curvature interference analysis method. The nonlinear equation system encountered in determining the curvature interference limit line is embedded into the ...
Shibo Mu   +8 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit   +11 more
wiley   +1 more source

A unified theory for nonparallel axis gears conjugate to involute cylindrical gears including face gears

open access: yesJournal of Advanced Mechanical Design, Systems, and Manufacturing
The purpose of this study is to clarify the meshing mechanisms of all gears conjugated with involute cylindrical gears, including configurations with nonparallel axes, and to bring these mechanisms into practical application.
Noritsugu MAEDA, Syuhei KUROKAWA
doaj   +1 more source

ANALYSIS OF LOAD-BEARING MESHING CHARACTERISTICS OF CYCLOIDAL PINWHEEL OF RV REDUCER BASED ON FINITE ELEMENT MODELING (MT)

open access: yesJixie qiangdu, 2023
In order to study the influence of load change on the meshing characteristics of cycloid pinwheel of RV reducer, considering the modification of cycloid tooth profile, the three-dimensional model of cycloid pinwheel mechanism was established by UG.
LIANG Qiang, CHENG Cheng, SHI BaoJun
doaj  

新型滤波减速器的效率分析及试验

open access: yesJixie chuandong, 2007
The meshing efficiency of the eccentric reducing mechanism and the filtering spline gear mechanism of a new type of filtering gear reducer (China patent CN1699793A) is analyzed.
潘继生, 梁锡昌, 王光建
doaj  

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