Results 81 to 90 of about 16,671 (265)
Generating golden Syrian hamsters with conditional alleles via zygote microinjection of CRISPR/Cas9
We established the first conditional knockout (cKO) model in the golden Syrian hamster by CRISPR/Cas9‐mediated genome editing. Cas9 protein, two sgRNAs, and a donor plasmid carrying loxP‐flanked exon 2 of the ApoF gene were microinjected into one‐cell embryos. The floxed allele was efficiently generated (up to 27%) and transmitted through the germline.
Wei Chen +16 more
wiley +1 more source
Hadži Prodanova Cave in western Serbia is a multilayered site which, in addition to Palaeolithic tools, has yielded a relatively rich fauna of small and large vertebrates. In this paper the rodent fauna from this site is described.
KATARINA BOGIĆEVIĆ +5 more
doaj +1 more source
Nanoformulated Diacerein Alleviates Hyperlipidemia via Gut Microbiota Modulation In Vivo
A nanoformulation of diacerein (Nano‐DIA) was fabricated with carboxymethyl cellulose, achieving enhanced solubility and rapid dissolution for alternative anti‐hyperlipidemia therapeutics. Mechanistic studies revealed its in vivo lipid‐lowering efficacy is through metabolite‐mediated and microbiota‐dependent manner, highlighting its dual action on host
Zheng Peng +8 more
wiley +1 more source
Prevention of Clostridium difficile infection in hamsters using a non-toxigenic strain
: The present study aimed to evaluate five non-toxigenic strains of Clostridium difficile (NTCD) in vitro and to select one strain to prevent C. difficile (CDI) infection in hamsters ( Mesocricetus auratus ).
Carlos Augusto de Oliveira Júnior +5 more
doaj +1 more source
Equine proliferative enteropathy--a review of recent developments. [PDF]
Equine proliferative enteropathy (EPE) is a disease of foals caused by the obligate intracellular organism Lawsonia intracellularis. This emerging disease affects mainly weanling foals and causes fever, lethargy, peripheral oedema, diarrhoea, colic and ...
Gebhart, CJ, Pusterla, N
core +1 more source
Validation of assays to monitor immune responses in the Syrian golden hamster (Mesocricetus auratus)
The Syrian golden hamster (Mesocricetus auratus) is a valuable but under-utilized animal model for studies of human viral pathogens such as bunyaviruses, arenaviruses, flaviviruses, henipaviruses, and SARS-coronavirus.
M. Zivcec +4 more
semanticscholar +1 more source
Work minimization accounts for footfall phasing in slow quadrupedal gaits [PDF]
Quadrupeds, like most bipeds, tend to walk with an even left/right footfall timing. However, the phasing between hind and forelimbs shows considerable variation.
Self Davies, Z T, Usherwood, J R
core +2 more sources
ABSTRACT Kalavan‐2, a high‐altitude (∼1640 m a.s.l.) open‐air site in Armenia, preserves stratified Middle Paleolithic occupations with a rich small‐vertebrate record. Luminescence dating has placed site formation between ~60 and 45 ka, but without independent chronological control of the microvertebrate accumulation.
Dominik L. Rogall +4 more
wiley +1 more source
Are Hibernators Toast? Global Climate Change and Prolonged Seasonal Hibernation
This review examines how global climate change impacts mammalian hibernators, emphasizing physiological, ecological and phenological aspects. Many hibernating species already inhabit extreme environments, thus are at risk as climate variability intensifies.
Kathrin H. Dausmann +1 more
wiley +1 more source
Data on Schistosoma mansoni-Entamoeba histolytica coinfection are scarce in the literature. In the present study, hamsters that had been infected for 70 days with Schistosoma mansoni (LE strain) were inoculated via the portal vein with two strains of ...
Silvio Santana Dolabella +5 more
doaj +1 more source

