Results 251 to 260 of about 64,865 (357)
Neural crest cell biology shapes lizard skull evolution across evolutionary time scales. [PDF]
Horta-Lacueva Q +7 more
europepmc +1 more source
ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao +16 more
wiley +1 more source
EpCAM supports exit from pluripotency of embryonic stem cells via Eomes. [PDF]
Gong N +10 more
europepmc +1 more source
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha +13 more
wiley +1 more source
Single-cell transcriptomics-informed induced pluripotent stem cells differentiation to tenogenic lineage. [PDF]
Papalamprou A +8 more
europepmc +1 more source
Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
Advances in the differentiation of induced pluripotent stem cells into vascular cells for the treatment of diabetic microvascular disease. [PDF]
Wang S +8 more
europepmc +1 more source
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu +11 more
wiley +1 more source
Why and How Are Infants with Hutchinson-Gilford Progeria Syndrome Born Without Severe Manifestations? [PDF]
Erokhina MA +3 more
europepmc +1 more source

