Results 281 to 290 of about 64,865 (357)
Molecular Basis and Clinical Spectrum of WNT10A‐Related Oligodontia
Clinical Genetics, Volume 110, Issue 1, Page 3-14, July 2026.Cellular Mechanism behind WNT10A phenotypes. ABSTRACT WNT10A mutations, a major genetic determinant of dental agenesis and ectodermal dysplasia, exert profound effects on craniofacial development. Although classified as rare disorders, these mutations account for more than half of oligodontia cases, reflecting their critical role.
Perennes Elise +5 more
wiley +1 more source
Genetic architecture of craniofacial morphogenesis: roles of <i>PAX3</i>, <i>PAX7</i>, and <i>PAX9</i>. [PDF]
Front Cell Dev BiolWang K, Li N, Liu W, Li YG, Ren F.
europepmc +1 more source
Cell Proliferation, Volume 59, Issue 7, July 2026.This review outlines kidney organoid differentiation strategies, key developmental mechanisms, and engineering and multi‐omics approaches driving their progress toward regenerative medicine. ABSTRACT Chronic kidney disease (CKD) has emerged as a critical public health challenge worldwide, and organ donor shortages underscore the urgent need for ...
Bohong Guo +9 more
wiley +1 more source
MIC-Drop-seq: scalable single-cell phenotyping of mutant vertebrate embryos. [PDF]
Nat CommunCarey CM +6 more
europepmc +1 more source
Proteolytic remodelling of the extracellular matrix by pericytes
The FEBS Journal, Volume 293, Issue 13, Page 3899-3953, July 2026.Pericytes are specialised perivascular cells intimately connected with endothelial cells and essential for the maintenance of vascular beds. They contribute to the formation and remodelling of the extracellular matrix by actively secreting proteases and protease inhibitors.
Tina Burkhard +4 more
wiley +1 more source
The FEBS Journal, Volume 293, Issue 13, Page 3954-3972, July 2026.Basement membrane (BM) homeostasis relies on a balance between integrity, controlled remodelling and pathological degradation. Increased protease expression beneath the BM, along with reduced levels of endogenous protease inhibitors, drives the transition from a continuous, protective barrier to a discontinuous interface.
Clara Legendre +2 more
wiley +1 more source
Embryonic mesenchyme, mesenchymal tumors and mesenchymal stem cells: need for clarification of cell types and standardization of biomedical terminology. [PDF]
Cell Mol Life SciWilting J, Becker J, Tsikolia N.
europepmc +1 more source
Journal of Neurochemistry, Volume 170, Issue 7, July 2026.The exceptional size of the human cerebral cortex reflects evolutionary changes in neural precursors (NPs), the cells that generate cortical neurons and glia. Pluripotent stem cell‐derived brain organoids now allow direct comparison of human, nonhuman primate, and rodent in the laboratory.
Wendy W. Y. Choi, Julien Muffat, Yun Li
wiley +1 more source
Rtf1-dependent transcriptional pausing regulates cardiogenesis. [PDF]
ElifeLangenbacher AD +10 more
europepmc +1 more source
Mapping the murine TMJ glenoid fossa over development, homeostasis and in response to disease
Journal of Anatomy, Volume 249, Issue 1, Page 85-96, July 2026.The fibrocartilage of the murine glenoid fossa and condyle of the temporomandibular joint are shown to form at distinct times with distinct molecular identities. Changes in the condyle during disease lead to remodelling of the fossa to maintain joint alignment.
Ticha Tuwatnawanit +4 more
wiley +1 more source