Results 91 to 100 of about 110,409 (295)
Small Structures, EarlyView.This article highlights the fibrous morphology of multiwalled carbon nanotubes as a key factor in their genotoxicity. Fibers physically interfere in cell division, generating binucleated cells and micronuclei, both of which are precursors of carcinogenesis.
Núria Pulido‐Artola +4 more
wiley +1 more source
Advances in the design and development of oncolytic measles viruses. [PDF]
, 2015 A successful oncolytic virus is one that selectively propagates and destroys cancerous tissue without causing excessive damage to the normal surrounding tissue. Oncolytic measles virus (MV) is one such virus that exhibits this characteristic and thus has
Hutzen, Brian +2 more
core +1 more source
Brain Pathology, EarlyView.ADAPTR recommendations for Adult‐type Diffuse Gliomas in Resource‐restrained settings. Abstract The fifth edition of the WHO classification of CNS Tumors (WHO CNS5) has revised the diagnostic and grading criteria for Adult‐type Diffuse Gliomas (ADGs) by integrating molecular parameters with histologic features.
Vani Santosh +11 more
wiley +1 more source
Einfluss der Art der Materialgewinnung auf die Diagnosefindung in der Lungenpathologie [PDF]
, 2019 Das Ziel der Arbeit ist die Darstellung der Möglichkeiten der Kryobiopsien für die Diagnostik von Lungenerkrankungen und Pleuraerkrankungen. Es wurde zunächst gezeigt, dass die transbronchialen Kryobiopsien einen deutlichen morphologischen Unterschied ...
Griff, Sergej
core +1 more source
Malignant craniopharyngiomas: Institutional experience and literature review
Brain Pathology, EarlyView.We report the second case of malignant craniopharyngioma with BAP1 and TP53 mutations. A literature review identified 44 cases of malignant craniopharyngiomas with a median overall survival of 6 months. Eighteen (41%) occurred in patients without any history of radiation, suggesting that mechanisms other than radiation have contributed to their ...
Thomas J. Auen +10 more
wiley +1 more source
Intercellular Communication in Malignant Pleural Mesothelioma: Properties of Tunneling Nanotubes
Frontiers in Physiology, 2014 Malignant pleural mesothelioma is a particularly aggressive and locally invasive malignancy with a poor prognosis despite advances in understanding of cancer cell biology and development of new therapies.
Justin William Ady +10 more
doaj +1 more source
The mechanism of iron binding processes in erionite fibres [PDF]
, 2017 Fibrous erionite-Na from Rome (Oregon, USA) was K-exchanged and characterized from the structural point of view. In addition, the modifications experienced after contact with a Fe(II) source were investigated for evaluating if the large potassium ions ...
Ballirano, Paolo +5 more
core +1 more source
British Journal of Pharmacology, EarlyView.Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy, inducing durable remissions in responding patients. However, they are associated with variable outcomes, spanning from disease hyperprogression to complete responses with the onset of immune‐related adverse events.
Mikhaël Attias, Ciriaco A. Piccirillo
wiley +1 more source
European Journal of Haematology, EarlyView.SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley +1 more source
Is Adenosine Deaminase in Pleural Fluid a Useful Marker for Differentiating Tuberculosis from Lung Cancer or Mesothelioma in Japan, a Country with Intermediate Incidence of Tuberculosis? [PDF]
, 2011 The objective of this study was to evaluate the utility of the determination of adenosine deaminase (ADA) level in pleural fluid for the differential diagnosis between tuberculous pleural effusion (TPE) and malignant pleural effusion (MPE) in Japan, a ...
Aoe, Keisuke +9 more
core +1 more source