Results 81 to 90 of about 64,353 (271)

Bilateral diffuse pulmonary infiltrates secondary to malignant peritoneal mesothelioma – A rare clinical presentation

open access: yesRespiratory Medicine Case Reports, 2019
Diffuse pulmonary metastasis secondary to primary peritoneal malignant mesothelioma is rarely reported in the literature. In this report we describe a 59-year-old Caucasian women with no known previous asbestos exposure presenting with bilateral diffuse ...
Madeleine Haygarth   +5 more
doaj   +1 more source

The Role of SAMHD1 in Viral Resistance and Transduction Efficiency Challenges in Pediatric Hematological Malignancies: Mechanistic Insights and Clinical Perspectives

open access: yesEuropean Journal of Haematology, EarlyView.
SAMHD1 regulates intracellular dNTP pools, influencing lentiviral transduction, gene therapy efficiency, and disease progression in pediatric hematological malignancies. Integrated bioinformatics and targeted strategies, including CRISPR and pharmacological inhibition, highlight its therapeutic potential.
Waseem Alzamzami
wiley   +1 more source

Improving Access and Recruitment to Clinical Trials for Lung Cancer Patients: A Multi‐Phase, Qualitative Focus Group and Co‐Production Study

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aim To design and develop a novel co‐produced intervention tool aimed at facilitating discussions that lung cancer nurses have with lung cancer patients about clinical trial opportunities; and promote trial recruitment. Design A multi‐phase qualitative focus group (phase 1) and co‐production (phase 2) study.
Christopher Dodd   +8 more
wiley   +1 more source

Cytoplasmic HuR Expression Enhances Chemoresistance in Pleural Mesothelioma Through Increased Expression of CALB2, Promotion of the E2F Pathway, and Suppression of the p53 Pathway

open access: yesThoracic Cancer
Introduction Chemotherapy is crucial for treating pleural mesothelioma; however, the outcomes are poor, necessitating an urgent need to study the mechanism of chemotherapy resistance in mesothelioma cells.
Susumu Kirimura   +6 more
doaj   +1 more source

Rethinking continuity in primary care for people with mesothelioma [PDF]

open access: bronze, 2023
Emilie Couchman   +3 more
openalex   +1 more source

Factors influencing malignant mesothelioma survival: a retrospective review of the National Mesothelioma Virtual Bank cohort [version 2; referees: 1 approved, 2 approved with reservations]

open access: yesF1000Research, 2018
Background: Malignant mesothelioma (MM) is a rare but deadly malignancy with about 3,000 new cases being diagnosed each year in the US.  Very few studies have been performed to analyze factors associated with mesothelioma survival, especially for ...
Waqas Amin   +4 more
doaj   +1 more source

Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer

open access: yesExperimental Physiology, EarlyView.
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge   +10 more
wiley   +1 more source

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