Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang +12 more
wiley +1 more source
Secured Hash2 based Message Authentication Code using GUI Controls
V RKulkarni +2 more
openalex +1 more source
A lightweight zero-trust authentication architecture for IoT via unified enhanced FAST-SM9 and dynamic re-authentication. [PDF]
Ma Z +5 more
europepmc +1 more source
This research deciphers the m6A transcriptome by profiling its sites and functional readout effects: from mRNA stability, translation to alternative splicing, across five different cell types. Machine learning model identifies novel m6A‐binding proteins DDX6 and FXR2 and novel m6A reader proteins FUBP3 and L1TD1.
Zhou Huang +11 more
wiley +1 more source
Secure TPMS Data Transmission in Real-Time IoV Environments: A Study on 5G and LoRa Networks. [PDF]
Niranjan DK, Supriya M, Tiberti W.
europepmc +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Lightweight authentication for IoT devices (LAID) in sustainable smart cities. [PDF]
Khalique A +3 more
europepmc +1 more source
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source
MBDS: MESSAGE AUTHENTICATION CODE (MAC) BASED BLACK HOLE DETECTION SYSTEM INMANET’S
S. Chaturya, Mrs.Y. Adilakshmi
openalex +1 more source
RINAsense: An open-source, low-power IoT sensor node for Recursive InterNetwork Architecture (RINA) Experimentation. [PDF]
Sarabia-Jácome D, Grasa E, Catalán M.
europepmc +1 more source

