Results 91 to 100 of about 977,339 (281)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad   +3 more
wiley   +1 more source

Issues of legal regulation of import substitution of messengers in the state and municipal service [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия «Экономика. Управление. Право»
Introduction. Today, in the Russian Federation the authorities face the task of transition to domestic digital solutions at all levels of government. This issue is especially relevant in the conditions of economic sanctions.
Plotnikov, Nikita V.
doaj   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

open access: yesAdvanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach   +7 more
wiley   +1 more source

Messengers (Olacari) and Ways of Communication in Moldavia (15th-17th Centuries) [PDF]

open access: yesCodrul Cosminului
The present paper is part of wider research on the history of communications and it is focused on some of the messengers in late Moldavian medieval society (15th– 17th centuries).
Adrian-Ionut Gilea
doaj   +1 more source

Solving The Muon g-2 Anomaly With Natural NMSSM From Generalized Deflected AMSB

open access: yes, 2017
We propose to realize (natural) NMSSM spectrum from deflected AMSB with new messenger-matter interactions. With additional messenger-matter interactions involving ${\bf 10}\oplus{\bf \overline{10}}$ representation messengers, the muon g-2 anomaly can be ...
Ning, Xuyang, Wang, Fei
core   +1 more source

Death messengers [PDF]

open access: yesBMJ, 2007
Mehra, M. R.   +2 more
openaire   +3 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

open access: yesAdvanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon   +21 more
wiley   +1 more source

Revisiting Signature of Minimal Gauge Mediation

open access: yes, 2007
We revisit phenomenology of the minimal gauge-mediated model. This model is motivated from the SUSY CP and flavor problems. A specific feature of this model is that \tan\beta is naturally large, since the B term in the Higgs potential is zero at the ...
Akeroyd   +39 more
core   +1 more source

Serotonergic System‐Targeted Nucleic Acid Hydrogel Coordinates Excitability Restoration and Circuit Reconstruction for Spinal Cord Injury Therapy

open access: yesAdvanced Materials, EarlyView.
The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li   +19 more
wiley   +1 more source

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