Results 1 to 10 of about 180 (70)

A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes

open access: yesNew Journal of Physics, 2021
We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles.
Denis S Grebenkov   +2 more
doaj   +1 more source

Pancreatic Beta Cell G-Protein Coupled Receptors and Second Messenger Interactions: A Systems Biology Computational Analysis. [PDF]

open access: yesPLoS ONE, 2016
Insulin secretory in pancreatic beta-cells responses to nutrient stimuli and hormonal modulators include multiple messengers and signaling pathways with complex interdependencies.
Leonid E Fridlyand, Louis H Philipson
doaj   +1 more source

Bipolar Disorder and Obsessive Compulsive Disorder Comorbidity [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2014
The comorbidity of bipolar disorder and anxiety disorders is a well known concept. Obsessive-compulsive disorder is the most commonly seen comorbid anxiety disorder in bipolar patients.
Necla Keskin, Lut Tamam
doaj   +1 more source

Water-soluble cranberry extract inhibits Vibrio cholerae biofilm formation possibly through modulating the second messenger 3', 5' - Cyclic diguanylate level. [PDF]

open access: yesPLoS ONE, 2018
Quorum sensing (QS) and nucleotide-based second messengers are vital signaling systems that regulate bacterial physiology in response to changing environments.
Daniel B Pederson   +4 more
doaj   +1 more source

Arsenic Trioxide Modulates the Central Snail Neuron Action Potential

open access: yesJournal of the Formosan Medical Association, 2009
The electropharmacological effect of arsenic trioxide (As2O3) is unknown. The present study investigated the effects of As2O3 on spontaneous neuronal impulse activity. Methods: Intracellular recordings and the two-electrode voltage clamp method were used
Guan-Ling Lu   +4 more
doaj   +1 more source

309 Measurement of agonist-induced calcium and mechanical signals in human airway smooth muscle cells

open access: yesJournal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: The goal of this proposal is to develop a technology that combines calcium imaging via confocal microscopy, and force measurement via monolayer stress microscopy to perform simultaneous quantitative measurements of agonist-induced Ca2 ...
Santina Johnson   +9 more
doaj   +1 more source

Artificial Signal Transduction

open access: yesChemistryOpen, 2020
Communication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto ...
Robert Bekus, Prof. Thomas Schrader
doaj   +1 more source

To be or not to be… Nicotinic acid adenine dinucleotide phosphate (NAADP): A new intracellular second messenger?

open access: yesBiological Research, 2004
Nicotinic acid adenine dinucleotide phosphate (NAADP) is a potent activator of intracellular Ca2+ release in several vertebrate and invertebrate systems.
EDUARDO NUNES CHINI
doaj   +1 more source

The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP

open access: yesFrontiers in Microbiology, 2021
RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria.
Yang Fu   +9 more
doaj   +1 more source

Nuclear expression of diacylglycerol kinases: possible involvement in DNA replication

open access: yesEuropean Journal of Histochemistry, 2009
The existence of intranuclear lipid-dependent signal transduction systems has been demonstrated by several independent groups. Remarkably, intranuclear lipid-dependent signal transduction pathways are regulated independently from their membrane/cytosolic
C Evangelisti   +5 more
doaj   +1 more source

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