Results 41 to 50 of about 130,287 (295)

Regulation of poly-GlcNAc expression and fimbriation in uropathogenic "E. coli" [PDF]

, 2013
The transition of planktonic to sessile lifestyles in bacteria rests upon a tightly controlled program that gets triggered by the environmental composition and whose implementation requires multiple feedback controls. Uropathogenic E.
Hosch, Lucie
core   +1 more source

Luciferase complementation based-detection of G-protein-coupled receptor activity

BioTechniques, 2018
Protein complementation assays (PCA) are used as pharmacological tools, enabling a wide array of applications, ranging from studies of protein–protein interactions to second messenger effects.
Hideaki Yano, Ning Sheng Cai, Jonathan A Javitch, Sergi Ferré   +3 more
doaj   +1 more source

Ceramide mediates radiation-induced germ cell apoptosis via regulating mitochondria function and MAPK factors in Caenorhabditis elegans

Ecotoxicology and Environmental Safety, 2021
Studies about radiation damage in vivo are very significant for healthy risk assessment as well as cancer radiotherapy. Ceramide as a second messenger has been found to be related to radiation-induced apoptosis. However, the detailed mechanisms in living
Yaning Yang, Guangmin Xu, Yun Xu, Xiaowen Cheng, Shengmin Xu, Shaopeng Chen, Lijun Wu   +6 more
doaj   +1 more source

Molecular Imaging Studies of Second Messenger Pathways: Looking Deeper than the Membrane

, 2012
The most successful applications of molecular imaging by PET include studies of energy metabolism, dopamine synthesis, transporters, and membrane-bound receptors.
Paul Cumming, Vasdev, Neil, Neil Vasdev, Cumming, Paul   +3 more
core   +1 more source

The period circadian clock 2 gene responds to glucocorticoids and regulates osteogenic capacity

Regenerative Therapy, 2019
Introduction: The central regulatory system that generates biological rhythms is regulated by circadian clock genes expressed by cells in the suprachiasmatic nucleus.
Takahiro Abe, Tomoya Sato, Tetsuya Yoda, Kazuto Hoshi   +3 more
doaj   +1 more source

LytTR Regulatory Systems: A potential new class of prokaryotic sensory system. [PDF]

PLoS Genetics, 2018
The most commonly studied prokaryotic sensory signal transduction systems include the one-component systems, phosphosignaling systems, extracytoplasmic function (ECF) sigma factor systems, and the various types of second messenger systems.
Zhengzhong Zou, Hua Qin, Amanda E Brenner, Rahul Raghavan, Jess A Millar, Qiang Gu, Zhoujie Xie, Jens Kreth, Justin Merritt   +8 more
doaj   +1 more source

Multiple Second-Messenger System Modulation of Voltage-Activated Calcium Currents in Teleost Retinal Horizontal Cells

, 1998
Pfeiffer-Linn, Cindy L. and Eric M. Lasater. Multiple second-messenger system modulation of voltage-activated calcium currents in teleost retinal horizontal cells. J. Neurophysiol. 80: 377–388, 1998.
Eric M. Lasater, Cindy L. Pfeiffer-Linn
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Roles of Nicotinamide Adenine Dinucleotide (NAD+) in Biological Systems

Challenges, 2018
NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways since it acts as a key regulator of cellular and organism homeostasis. NAD+ is a coenzyme in redox reactions, a donor of adenosine diphosphate-ribose (ADPr) moieties in ADP-
Palmiro Poltronieri, Nataša Čerekovic
doaj   +1 more source

Emerging Concepts on the Role of ADP-Ribosylation

Challenges, 2020
NAD+ has emerged as a crucial element in both bioenergetic and signaling pathways, since it acts as a key regulator of cellular and organism homeostasis.
Palmiro Poltronieri
doaj   +1 more source