Results 21 to 30 of about 2,212 (248)
Journal of Clinical and Translational Science, 2023 OBJECTIVES/GOALS: The goal of this proposal is to develop a technology that combines calcium imaging via confocal microscopy, and force measurement via monolayer stress microscopy to perform simultaneous quantitative measurements of agonist-induced Ca2 ...
Santina Johnson +9 more
doaj +1 more source
Arsenic Trioxide Modulates the Central Snail Neuron Action Potential
Journal of the Formosan Medical Association, 2009 The electropharmacological effect of arsenic trioxide (As2O3) is unknown. The present study investigated the effects of As2O3 on spontaneous neuronal impulse activity. Methods: Intracellular recordings and the two-electrode voltage clamp method were used
Guan-Ling Lu +4 more
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Artificial Signal Transduction
ChemistryOpen, 2020 Communication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto ...
Robert Bekus, Prof. Thomas Schrader
doaj +1 more source
Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]
, 2013 Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören +27 more
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Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]
, 2013 Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
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Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
, 2016 Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Fucile, Geoffrey +6 more
core +1 more source
The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP
Frontiers in Microbiology, 2021 RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria.
Yang Fu +9 more
doaj +1 more source
Analysis of cyclic di-GMP signaling components in "caulobacter crescentus" behavior and cell cycle control [PDF]
, 2013 Cell cycle progression and polar morphogenesis in Caulobacter crescentus are coordinated by the interplay of multiple proteins in time and space. One major regulatory factor is the second messenger cyclic di-GMP (c-di-GMP) therefore especially the ...
Friedrich, Elvira
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Second Messenger Systems in Human Gliomas
Archives of Pathology & Laboratory Medicine, 2007 Abstract Context. —Patients with glioblastoma (astrocytoma, World Health Organization grade IV) exhibit 2-year survival rates of less than 20% despite significant advances in therapeutic options available to patients.
Roger E, McLendon +3 more
openaire +2 more sources