Results 21 to 30 of about 130,287 (295)

Recent advances and perspectives in nucleotide second messenger signaling in bacteria. [PDF]

open access: yes, 2023
Nucleotide second messengers act as intracellular 'secondary' signals that represent environmental or cellular cues, i.e. the 'primary' signals. As such, they are linking sensory input with regulatory output in all living cells. The amazing physiological
Tschowri, N.   +9 more
core   +2 more sources

A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes

open access: yesNew Journal of Physics, 2021
We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles.
Denis S Grebenkov   +2 more
doaj   +1 more source

Bipolar Disorder and Obsessive Compulsive Disorder Comorbidity [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2014
The comorbidity of bipolar disorder and anxiety disorders is a well known concept. Obsessive-compulsive disorder is the most commonly seen comorbid anxiety disorder in bipolar patients.
Necla Keskin, Lut Tamam
doaj   +1 more source

Arsenic Trioxide Modulates the Central Snail Neuron Action Potential

open access: yesJournal of the Formosan Medical Association, 2009
The electropharmacological effect of arsenic trioxide (As2O3) is unknown. The present study investigated the effects of As2O3 on spontaneous neuronal impulse activity. Methods: Intracellular recordings and the two-electrode voltage clamp method were used
Guan-Ling Lu   +4 more
doaj   +1 more source

309 Measurement of agonist-induced calcium and mechanical signals in human airway smooth muscle cells

open access: yesJournal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: The goal of this proposal is to develop a technology that combines calcium imaging via confocal microscopy, and force measurement via monolayer stress microscopy to perform simultaneous quantitative measurements of agonist-induced Ca2 ...
Santina Johnson   +9 more
doaj   +1 more source

Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]

open access: yes, 2013
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören   +27 more
core   +1 more source

Artificial Signal Transduction

open access: yesChemistryOpen, 2020
Communication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto ...
Robert Bekus, Prof. Thomas Schrader
doaj   +1 more source

Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]

open access: yes, 2013
Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
core   +1 more source

Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]

open access: yes, 2016
Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Fucile, Geoffrey   +6 more
core   +1 more source

The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP

open access: yesFrontiers in Microbiology, 2021
RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria.
Yang Fu   +9 more
doaj   +1 more source

Home - About - Disclaimer - Privacy