Results 21 to 30 of about 130,287 (295)
Recent advances and perspectives in nucleotide second messenger signaling in bacteria. [PDF]
Nucleotide second messengers act as intracellular 'secondary' signals that represent environmental or cellular cues, i.e. the 'primary' signals. As such, they are linking sensory input with regulatory output in all living cells. The amazing physiological
Tschowri, N. +9 more
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We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles.
Denis S Grebenkov +2 more
doaj +1 more source
Bipolar Disorder and Obsessive Compulsive Disorder Comorbidity [PDF]
The comorbidity of bipolar disorder and anxiety disorders is a well known concept. Obsessive-compulsive disorder is the most commonly seen comorbid anxiety disorder in bipolar patients.
Necla Keskin, Lut Tamam
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Arsenic Trioxide Modulates the Central Snail Neuron Action Potential
The electropharmacological effect of arsenic trioxide (As2O3) is unknown. The present study investigated the effects of As2O3 on spontaneous neuronal impulse activity. Methods: Intracellular recordings and the two-electrode voltage clamp method were used
Guan-Ling Lu +4 more
doaj +1 more source
OBJECTIVES/GOALS: The goal of this proposal is to develop a technology that combines calcium imaging via confocal microscopy, and force measurement via monolayer stress microscopy to perform simultaneous quantitative measurements of agonist-induced Ca2 ...
Santina Johnson +9 more
doaj +1 more source
Bi-modal distribution of the second messenger c-di-GMP controls cell fate and asymmetry during the caulobacter cell cycle [PDF]
Many bacteria mediate important life-style decisions by varying levels of the second messenger c-di-GMP. Behavioral transitions result from the coordination of complex cellular processes such as motility, surface adherence or the production of virulence ...
Abel, Sören +27 more
core +1 more source
Artificial Signal Transduction
Communication between and inside cells as well as their response to external stimuli relies on elaborated systems of signal transduction. They all require a directional transmission across membranes, often realized by primary messenger docking onto ...
Robert Bekus, Prof. Thomas Schrader
doaj +1 more source
Folding of the transcription factor Brinker and interactions of the bacterial second messenger c-di-GMP studied by NMR [PDF]
Nuclear magnetic resonance (NMR) spectroscopy is a technique, which allows the non-invasive investigation of structures, dynamics and interactions of biomolecules.
Gentner, Martin
core +1 more source
Cyclic di-GMP mediates a histidine kinase/phosphatase switch by noncovalent domain cross-linking [PDF]
Histidine kinases are key components of regulatory networks in bacteria. Although many of these enzymes are bifunctional, mediating both phosphorylation and dephosphorylation of downstream targets, the molecular details of this central regulatory switch ...
Fucile, Geoffrey +6 more
core +1 more source
The Multiple Regulatory Relationship Between RNA-Chaperone Hfq and the Second Messenger c-di-GMP
RNA chaperone protein Hfq is an important post-transcriptional regulator in bacteria, while c-di-GMP is a second messenger signaling molecule widely distributed in bacteria.
Yang Fu +9 more
doaj +1 more source

