Results 101 to 110 of about 977,339 (281)

Genre of “Promise” as a Reflection of Intentional and Linguistic Organization in Virtual Pedagogical Discourse

open access: yesНаучный диалог
This research is situated within the context of contemporary discourse studies. It examines the genre of “promise” functioning within virtual pedagogical discourse.
T. G. Rabenko, E. S. Denisova
doaj   +1 more source

‘The Dung-heap and the Flower’: Gissing’s Nether World

open access: yesCahiers Victoriens et Edouardiens, 2005
This paper examines the creative dynamic behind Gissing’s most successful slum novel, The Nether World, by speculating on Gissing’s own ‘nether world’: in particular, his social disgrace following his conviction for petty theft at Owens College ...
Nigel Messenger
doaj   +1 more source

The pMSSM Interpretation of LHC Results Using Rernormalization Group Invariants

open access: yes, 2012
The LHC has started to constrain supersymmetry-breaking parameters by setting bounds on possible colored particles at the weak scale. Moreover, constraints from Higgs physics, flavor physics, the anomalous magnetic moment of the muon, as well as from ...
A. Djouadi   +6 more
core   +1 more source

Organic Light‐Emitting Diode in Phototherapy Applications

open access: yesAdvanced Photonics Research, EarlyView.
This article systematically reviews the development of organic light‐emitting diodes (OLEDs) in phototherapy, constructs a technical framework, and establishes a multidimensional knowledge graph encompassing indications, wavelengths, and light intensity.
Yingguang Zhu   +9 more
wiley   +1 more source

Automated classification of MESSENGER plasma observations via unsupervised transfer learning

open access: yesFrontiers in Astronomy and Space Sciences
Our methodology demonstrates a proof of concept of the applicability of transfer learning for heliophysics, a machine learning technique where knowledge learned from one task is reused to perform a similar unsupervised learning task with additional fine ...
Vicki Toy-Edens   +4 more
doaj   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu   +14 more
wiley   +1 more source

Orta Asya İlk Türk Devletlerinde Haberleşme Yöntemleri

open access: yesJournal of Universal History Studies
Türkler, ilk olarak Orta Asya’da tarih sahnesine çıkmışlar ve dünyanın farklı bölgelerine yayılmışlardır. Türkler, iç işlerinde ve dış ilişkilerinde kendilerine özgü haberleşme yöntemleri geliştirmişlerdir.
Mehmet Mandaloğlu
doaj   +1 more source

Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis

open access: yesAdvanced Science, EarlyView.
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang   +16 more
wiley   +1 more source

Metabolic Messengers: ceramides

open access: yesNature Metabolism, 2019
Ceramides are products of metabolism that accumulate in individuals with obesity or dyslipidaemia and alter cellular processes in response to fuel surplus. Their actions, when prolonged, elicit the tissue dysfunction that underlies diabetes and heart disease.
Scott A. Summers   +2 more
openaire   +3 more sources

DRD2 Deficiency Underlies Pituitary Adenoma Dependent on Escherichia coli Translocation from the Gut

open access: yesAdvanced Science, EarlyView.
Dopamine receptor D2 (DRD2) deficiency disrupts epithelial barrier integrity in both the gut and pituitary gland, facilitating translocation of gut‐derived Escherichia coli into pituitary tissue. Intratumoral E. coli are phagocytosed by microglia, triggering GSDMD‐dependent pyroptosis and HMGB1 release, which subsequently activates MAPK signaling to ...
Xian‐jun Su   +16 more
wiley   +1 more source

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