Mechanically Regulated Nanozymes for Remote Metabolic Reprogramming and Precise Cancer Therapy
Inspired by mechanoenzymes, a ferrocene‐based mechanically regulated nanozyme converts acoustic shear force into enhanced peroxidase‐like activity by decreasing electron density and alleviating steric hindrance at the Fe active sites, thereby rewiring redox homeostasis. Leveraging this remote regulatory mechanism, a multienzyme‐regulated nanoreactor is
Fangman Chen +13 more
wiley +2 more sources
Research Advances in Pheromone Biosynthesis Regulation via the PBAN Signaling Pathway in Insects. [PDF]
Zhang Y +7 more
europepmc +1 more source
Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley +1 more source
Preschoolers' Early Sentence Comprehension: Comparing Bilingual and Monolingual Children and the Role of Executive Function and Vocabulary Development. [PDF]
Rodenhurst N, Messenger K.
europepmc +1 more source
Nanodiamonds as Bioactive Platforms to Modulate Microbial, Mammalian, and Vertebrate Systems
Nanodiamonds (NDs) are biocompatible and antibacterial nanomaterials that support mammalian cell growth while inhibiting bacterial pathogens. NDs showed strong antibacterial activity, with Escherichia coli being more sensitive than Staphylococcus aureus. At 10 mg/mL, both bacteria exhibited ~8% viability.
Aaqil Rifai +6 more
wiley +1 more source
Beyond cargo clearance: p62 coordinates cAMP signalling and autophagy to drive cell fate decisions in <i>Dictyostelium discoideum</i>. [PDF]
Gautam S, Saran S.
europepmc +1 more source
We developed an assay to distinguish cellular binding from internalization. Compatible with microscopy and high‐throughput screening, the method identifies ligand‐mediated uptake. Applying top candidates to a protein‐based DNA carrier enhanced transfection efficiency, providing a rational strategy to improve non‐viral gene delivery systems.
David Scherer +5 more
wiley +1 more source
Feasibility of portable telemedicine devices for ambulance-based prehospital triage: a comparative simulation study. [PDF]
Kingma SL +9 more
europepmc +1 more source
Psychometric and Molecular Profiling to Predict Outcomes of Spinal Cord Stimulation for Chronic Pain: A Pilot Study. [PDF]
D'Agnelli S +8 more
europepmc +1 more source
ITC-Net-MingledApp: A comprehensive dataset of mixed mobile application traffic for network traffic classification in diverse environments. [PDF]
Rezaei Khesal A +5 more
europepmc +1 more source

