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RNA-Based Therapies for Hypercholesterolemia and Coronary Artery Disease. [PDF]
Lopez Mendoza MJ +5 more
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Atopic dermatitis-messengers, second messengers and cytokines
Clinical and Experimental Dermatology, 1993Atopic dermatitis (AD) shows many complex and interacting abnormalities of pharmacology, immunology and cellular control. Recent research in atopy has concentrated on abnormalities of cytokine production by T-helper cells. It is possible that cytokine imbalance causes many of the pharmacological and immunological changes seen in the disease.
openaire +2 more sources
Trends in Neurosciences, 2001
Notions of what constitutes a neurotransmitter have changed markedly with the advent in the past decade of synaptic molecules, which satisfy key neurotransmitter criteria but differ radically from classical transmitters. Thus, NO and carbon monoxide are neither stored in synaptic vesicles nor released by exocytosis.
D E, Barañano, C D, Ferris, S H, Snyder
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Notions of what constitutes a neurotransmitter have changed markedly with the advent in the past decade of synaptic molecules, which satisfy key neurotransmitter criteria but differ radically from classical transmitters. Thus, NO and carbon monoxide are neither stored in synaptic vesicles nor released by exocytosis.
D E, Barañano, C D, Ferris, S H, Snyder
openaire +2 more sources
Crosstalking second messengers
Nature Microbiology, 2020By competing for the same binding site on SmbA, a regulatory nucleotide-binding protein, the bacterial second messengers c-di-GMP and (p)ppGpp inversely balance cell cycle re-entry of growth-arrested swarmer cells of Caulobacter crescentus.
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Metabolic Messengers: itaconate
Nature MetabolismThe metabolite itaconate has emerged as an important immunoregulator with roles in antibacterial defence, inhibition of inflammation and, more recently, as an inhibitory factor in obesity. Itaconate is one of the most upregulated metabolites in inflammatory macrophages.
A. F. McGettrick +3 more
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