Issues of legal regulation of import substitution of messengers in the state and municipal service [PDF]
Известия Саратовского университета. Новая серия: Серия «Экономика. Управление. Право»Introduction. Today, in the Russian Federation the authorities face the task of transition to domestic digital solutions at all levels of government. This issue is especially relevant in the conditions of economic sanctions.
Plotnikov, Nikita V.
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Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Der chinesische Messenger WeChat: Praktiken der Automatisierung
Interkulturelles Forum der deutsch-chinesischen KommunikationIm Beitrag werden Praktiken der Automatisierung in der führenden chinesischen Messaging-Applikation WeChat untersucht. Die Applikation unterliegt ständigem Wandel, und die bisherigen Beschreibungen (v. a.
Szurawitzki Michael
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Messengers (Olacari) and Ways of Communication in Moldavia (15th-17th Centuries) [PDF]
Codrul CosminuluiThe present paper is part of wider research on the history of communications and it is focused on some of the messengers in late Moldavian medieval society (15th– 17th centuries).
Adrian-Ionut Gilea
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
DIGITAL ETIQUETTE IN BUSINESS COMMUNICATION: TYPICAL MISTAKES AND WAYS TO PREVENT THEM
Известия Южного федерального университета: Филологические наукиDigital technologies are gaining more and more popularity in a person's life and radically affect the communication process. It is necessary to create appropriate limits (norms and rules of etiquette behaviour) in the business communication.
Tatyana A. Litvyakova +1 more
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Hadis Kaynakları Bağlamında Garânîk Rivayetleri
Diyanet İlmi DergiBazı rivayetlere göre Resûlullah (s.a.s.) Necm Sûresini Kâbe yanında okurken şeytan bir yolunu bulup kendisine ait bir cümleyi âyetmiş gibi ilkâ etmiştir.
Ufuk Dağlıoğlu
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Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Right Relation with Tobacco: Decommercialization and Reverence
ZygonThe much-maligned tobacco plant has been exploited to kill more people than any other plant, with yearly tobacco deaths exceeding eight million globally.
Yogi Hendlin
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