Results 41 to 50 of about 390,536 (265)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A comparative study of the concept of "apostle" In the Holy Qur'an and the New Testament [PDF]

open access: yesComparative Theology, 2018
Introduction: The present article seeks to first examine the concept of "apostle" in the sacred texts of the two religions i.e. Christianity and Islam: the New Testament and the Holy Qur'an, and then, in a comparative approach, tries to identify the ...
Rasoul Razavi, Majid Hadizadeh
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Prospects of using social networks as part of innovative management to support professional communities in the development of the construction industry (on the example of the community of painters)

open access: yesInnovation and Sustainability
The article analyzes social networks and their role in the modern world as a key tool for uniting social groups of builders of various specialties. It has been found that social networks provide convenient and fast communication between specialists ...
S. Murha
doaj   +1 more source

Issues of legal regulation of import substitution of messengers in the state and municipal service [PDF]

open access: yesИзвестия Саратовского университета. Новая серия: Серия «Экономика. Управление. Право»
Introduction. Today, in the Russian Federation the authorities face the task of transition to domestic digital solutions at all levels of government. This issue is especially relevant in the conditions of economic sanctions.
Plotnikov, Nikita V.
doaj   +1 more source

The stela of Nedjemankh [PDF]

open access: yesMağallaẗ Markaz Al-H̲idmaẗ Lil Istišarāt Al-Baḥṯiyyaẗ wa Al-Luġāt, 2019
The cemetery to the south-west of the Dendara temple comprises burials from the Old Kingdom through to the Roman Period. In one of these burials dating to the Greco-Roman Period, a stela was discovered belonging to Nedjemankh, son of Pa-di-Harsomtus and ...
Ayman Wahby Taher Taher
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Metamorphoses of electronic nomad games: from a banal show to an existential drama / Метаморфозы игр электронного кочевника: от банального шоу к экзистенциальной драме

open access: yesИндустрии впечатлений: Технологии социокультурных исследований
The object of the study is an electronic nomad who creates and posts elements of their own existential spectacle on messenger channels and social media pages.
Elena Iakovleva / Елена Людвиговна Яковлева
doaj   +1 more source

Messengers (Olacari) and Ways of Communication in Moldavia (15th-17th Centuries) [PDF]

open access: yesCodrul Cosminului
The present paper is part of wider research on the history of communications and it is focused on some of the messengers in late Moldavian medieval society (15th– 17th centuries).
Adrian-Ionut Gilea
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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