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Matrices Activated with Messenger RNA

open access: yesJournal of Functional Biomaterials, 2023
Over two decades of preclinical and clinical experience have confirmed that gene therapy-activated matrices are potent tools for sustained gene modulation at the implantation area.
Raquel Martinez-Campelo   +1 more
doaj   +3 more sources

Who discovered messenger RNA? [PDF]

open access: yesCurrent Biology, 2015
The announcement of the discovery of messenger RNA (mRNA) and the cracking of the genetic code took place within weeks of each other in a climax of scientific excitement during the summer of 1961. Although mRNA is of decisive importance to our understanding of gene function, no Nobel Prize was awarded for its discovery.
M. Cobb
openaire   +5 more sources

Nuclear Export of Messenger RNA [PDF]

open access: yesGenes, 2015
Transport of messenger RNA (mRNA) from the nucleus to the cytoplasm is an essential step of eukaryotic gene expression. In the cell nucleus, a precursor mRNA undergoes a series of processing steps, including capping at the 5' ends, splicing and cleavage/polyadenylation at the 3' ends.
J. Katahira
openaire   +4 more sources

Decoding bioactive signals of the RNA secretome: the cell-free messenger RNA catalogue [PDF]

open access: yesExpert Reviews in Molecular Medicine
Despite gene-expression profiling being one of the most common methods to evaluate molecular dysregulation in tissues, the utilization of cell-free messenger RNA (cf-mRNA) as a blood-based non-invasive biomarker analyte has been limited compared to other
Rhys E. De Sota   +3 more
doaj   +2 more sources

Hypertensive crisis following mRNA COVID-19 vaccination in adolescents: two case reports [PDF]

open access: yesChildhood Kidney Diseases, 2022
In response to the global coronavirus disease 2019 (COVID-19) pandemic, vaccines were developed and approved quickly. However, numerous cardiovascular adverse events have been reported.
Myung Hyun Cho, Hae Il Cheong
doaj   +1 more source

Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts.

open access: yesPLoS Pathogens, 2021
Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus.
Molly R Braun   +6 more
doaj   +1 more source

Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients.

open access: yesJournal of the American Medical Association (JAMA), 2021
Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients Immunocompromised individuals have been excluded from studies of SARS-CoV-2 messenger RNA (mRNA) vaccines.
B. Boyarsky   +6 more
semanticscholar   +1 more source

Co-regulatory network of transcription factor and microrna: A key player of gene regulation

open access: yesBiomedical and Biotechnology Research Journal, 2021
Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA ...
Akshara Pande
doaj   +1 more source

Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

open access: yesTechnology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM   +7 more
doaj   +1 more source

Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer

open access: yesJAMA Oncology, 2021
Key Points Question Do patients with cancer develop adequate antibody responses to messenger RNA SARS-CoV-2 vaccines? Findings In this cohort study that included 102 patients with cancer who were receiving active treatment and 78 healthy controls, 92 ...
Amir Massarweh   +14 more
semanticscholar   +1 more source

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