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Matrices Activated with Messenger RNA [PDF]

open access: yesJournal of Functional Biomaterials, 2023
Over two decades of preclinical and clinical experience have confirmed that gene therapy-activated matrices are potent tools for sustained gene modulation at the implantation area.
Raquel Martinez-Campelo   +1 more
doaj   +4 more sources

Hypertensive crisis following mRNA COVID-19 vaccination in adolescents: two case reports [PDF]

open access: yesChildhood Kidney Diseases, 2022
In response to the global coronavirus disease 2019 (COVID-19) pandemic, vaccines were developed and approved quickly. However, numerous cardiovascular adverse events have been reported.
Myung Hyun Cho, Hae Il Cheong
doaj   +1 more source

Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts.

open access: yesPLoS Pathogens, 2021
Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus.
Molly R Braun   +6 more
doaj   +1 more source

Co-regulatory network of transcription factor and microrna: A key player of gene regulation

open access: yesBiomedical and Biotechnology Research Journal, 2021
Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA ...
Akshara Pande
doaj   +1 more source

Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

open access: yesTechnology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM   +7 more
doaj   +1 more source

HIV mRNA Vaccines—Progress and Future Paths

open access: yesVaccines, 2021
The SARS-CoV-2 pandemic introduced the world to a new type of vaccine based on mRNA encapsulated in lipid nanoparticles (LNPs). Instead of delivering antigenic proteins directly, an mRNA-based vaccine relies on the host’s cells to manufacture protein ...
Zekun Mu   +2 more
doaj   +1 more source

Identification and Characterization of mRNA and lncRNA Expression Profiles in Age-Related Hearing Loss [PDF]

open access: yesClinical and Experimental Otorhinolaryngology, 2023
Objectives Age-related hearing loss (ARHL), or presbycusis, is caused by disorders of sensory hair cells and auditory neurons. Many studies have suggested that the accumulation of mitochondrial DNA damage, the production of reactive oxygen species, noise,
Janghyun Kim   +5 more
doaj   +1 more source

Real-Time Messenger RNA Dynamics in Bacillus subtilis

open access: yesFrontiers in Microbiology, 2021
Messenger RNA molecules have been localized to different positions in cells and have been followed by time-lapse microscopy. We have used MS2-mVenus–labeled mRNA and single-particle tracking to obtain information on the dynamics of single-mRNA molecules ...
Laura Sattler, Peter L. Graumann
doaj   +1 more source

The Aberrant Expression of MicroRNA-125a-5p/IGF2BP3 Axis in Advanced Gastric Cancer and Its Clinical Relevance

open access: yesTechnology in Cancer Research & Treatment, 2020
RNA-binding proteins have been associated with cancer development. The overexpression of a well-known RNA-binding protein, insulin-like growth factor 2 messenger RNA–binding protein 3, has been identified as an indicator of poor prognosis in patients ...
Jing Zhang MS   +4 more
doaj   +1 more source

François Gros: from antibiotics to messenger RNA

open access: yesComptes Rendus Biologies, 2023
François Gros was a prominent French Molecular Biologist who made a major contribution to the discovery of messenger RNA in 1961. He pursued outstanding research on bacterial mRNA and its translation into proteins followed by pioneering work on muscle ...
Yaniv, Moshe
doaj   +1 more source

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