Results 1 to 10 of about 1,593,615 (383)

Matrices Activated with Messenger RNA

Journal of Functional Biomaterials, 2023
Over two decades of preclinical and clinical experience have confirmed that gene therapy-activated matrices are potent tools for sustained gene modulation at the implantation area.
Raquel Martinez-Campelo, Marcos Garcia-Fuentes   +1 more
doaj   +3 more sources

Decoding bioactive signals of the RNA secretome: the cell-free messenger RNA catalogue [PDF]

Expert Reviews in Molecular Medicine
Despite gene-expression profiling being one of the most common methods to evaluate molecular dysregulation in tissues, the utilization of cell-free messenger RNA (cf-mRNA) as a blood-based non-invasive biomarker analyte has been limited compared to other
Rhys E. De Sota, Stephen R. Quake, John J. Sninsky, Shusuke Toden   +3 more
doaj   +2 more sources

Hypertensive crisis following mRNA COVID-19 vaccination in adolescents: two case reports [PDF]

Childhood Kidney Diseases, 2022
In response to the global coronavirus disease 2019 (COVID-19) pandemic, vaccines were developed and approved quickly. However, numerous cardiovascular adverse events have been reported.
Myung Hyun Cho, Hae Il Cheong
doaj   +1 more source

Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients.

Journal of the American Medical Association (JAMA), 2021
Immunogenicity of a Single Dose of SARS-CoV-2 Messenger RNA Vaccine in Solid Organ Transplant Recipients Immunocompromised individuals have been excluded from studies of SARS-CoV-2 messenger RNA (mRNA) vaccines.
B. Boyarsky, William Werbel, R. Avery, A. Tobian, A. Massie, D. Segev, J. Garonzik‐Wang   +6 more
semanticscholar   +1 more source

Respiratory syncytial virus M2-1 protein associates non-specifically with viral messenger RNA and with specific cellular messenger RNA transcripts.

PLoS Pathogens, 2021
Respiratory syncytial virus (RSV) is a major cause of respiratory disease in infants and the elderly. RSV is a non-segmented negative strand RNA virus.
Molly R Braun, Sarah L Noton, Emmeline L Blanchard, Afzaal Shareef, Philip J Santangelo, W Evan Johnson, Rachel Fearns   +6 more
doaj   +1 more source

Co-regulatory network of transcription factor and microrna: A key player of gene regulation

Biomedical and Biotechnology Research Journal, 2021
Transcription factor (TF) and microRNA (miRNA) interaction plays a vital role in the regulation of biological networks. TFs and miRNAs control the gene expression: TF at transcriptional level by affecting the messenger RNA (mRNA) transcription and miRNA ...
Akshara Pande
doaj   +1 more source

Construction of a circRNA-miRNA-mRNA Regulated Pathway Involved in EGFR-TKI Lung Adenocarcinoma Resistance

Technology in Cancer Research & Treatment, 2021
Objectives: Epidermal growth factor receptor-tyrosine kinase inhibitors are widely used for lung epidermal growth factor receptor-positive lung adenocarcinomas, but acquired resistance is inevitable.
Chenyue Dai MM, Bing Liu MD, Shaolei Li PhD, Yang Hong PhD, Jiahui Si PhD, Ying Xiong MSc, Nan Wu MD, Yuanyuan Ma PhD   +7 more
doaj   +1 more source

Evaluation of Seropositivity Following BNT162b2 Messenger RNA Vaccination for SARS-CoV-2 in Patients Undergoing Treatment for Cancer

JAMA Oncology, 2021
Key Points Question Do patients with cancer develop adequate antibody responses to messenger RNA SARS-CoV-2 vaccines? Findings In this cohort study that included 102 patients with cancer who were receiving active treatment and 78 healthy controls, 92 ...
Amir Massarweh, N. Eliakim‐Raz, A. Stemmer, A. Levy-Barda, S. Yust-Katz, A. Zer, A. Benouaich‐Amiel, H. Ben‐Zvi, N. Moskovits, B. Brenner, J. Bishara, D. Yahav, B. Tadmor, T. Zaks, S. Stemmer   +14 more
semanticscholar   +1 more source

François Gros: from antibiotics to messenger RNA

Comptes Rendus Biologies, 2023
François Gros was a prominent French Molecular Biologist who made a major contribution to the discovery of messenger RNA in 1961. He pursued outstanding research on bacterial mRNA and its translation into proteins followed by pioneering work on muscle ...
Yaniv, Moshe
doaj   +1 more source

Assessment of 4 Doses of SARS-CoV-2 Messenger RNA–Based Vaccine in Recipients of a Solid Organ Transplant

JAMA Network Open, 2021
This case series study assesses whether a fourth dose of a SARS-CoV-2 messenger RNA (mRNA)–based vaccine is associated with improved anti–SARS-CoV-2 antibody response in solid organ transplant recipients in France.
N. Kamar, F. Abravanel, O. Marion, R. Romieu-Mourez, Chloé Couat, A. Del Bello, J. Izopet   +6 more
semanticscholar   +1 more source