Results 101 to 110 of about 413,432 (237)

Metástases hepáticas como apresentação inicial de neoplasia oculta

open access: yes
A dor abdominal em idosos, especialmente quando inespecífica e sem sinais de alarme, pode ocultar diagnósticos graves. Metástases hepáticas frequentemente são a apresentação inicial de tumores sólidos, mas podem passar despercebidas em quadros clínicos ...
Takahasi, Bianca Namie Abe   +2 more
core   +1 more source

Metástases em corpo ciliar e íris em paciente com neoplasia de mama

open access: yes, 2023
Contexto: Pacientes com neoplasia de mama podem desenvolver metástases oculares, porem trata-se de uma entidade rara. Apesar da raridade desta patologia é importante suspeitar do diagnóstico caso a paciente apresente queixas ...
Fantin , Sabrina Mello   +4 more
core  

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Acompanhamento de longo prazo após a ressecção de metástases na tiroide de carcinoma hepatocelular em fígado cirrótico

open access: yes, 2013
Thyroid metastasis from hepatocellular carcinoma (HCC) is rare, and has poor prognosis. We report the case of a 62-year-old woman seen at our clinic because of the occurrence of a slightly painful abdominal mass.
Silva,Ivonete Sandra de Souza e   +17 more
core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

TIPOS HISTOPATOLÓGICOS QUE CAUSARAM METÁSTASES EM NEOPLASIAS MAMÁRIAS CANINAS

open access: yes, 2015
A metástase é maior causa de morte de pacientes com câncer. É um processo complexo de várias etapas que se inicia com a ruptura da membrana basal pela célula tumoral invadindo o tecido adjacente.
CALAZANS, Sabryna   +8 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

Metastatic primary lung tumor in three dogs
Tumor primário pulmonar metastático em três cães

open access: yesSemina: Ciências Agrárias, 2012
Primary lung tumors (PLT) are uncommon in dogs and occasionally metastasize to distant organs. This report describes three cases of PLT in dogs with epithelial origin, diagnosed post mortem through histopathology and immunohistochemistry.
Antônio Carlos Faria dos Reis   +4 more
doaj  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Tratamento de metástases hepáticas de carcinoma colo-rectal

open access: yes, 2009
Trabalho final do 6 ano médico com vista à atribuição do grau de mestre no âmbito do ciclo de estudos de mestrado integrado em medicina apres. à Faculdade de Medicina de Coimbra.O carcinoma colo-rectal é responsável por mais de 75% das metástases ...
Martins, Rui Miguel Rua Filipe
core  

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