Results 141 to 150 of about 407,464 (291)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Metástases na coluna vertebral

Coluna/Columna, 2010
Albert Vincent Berthier Brasil
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Carcinoma de células de transição da uretra com metástases cardíaca e pulmonar em cão

, 2000
Rogéria Serákides, Milene Alvarenga Rachid, J.C. Veado, J.M.C. Menezes   +3 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

CIRURGIA CITORREDUTORA (CRS) E QUIMIOTERAPIA INTRAPERITONEAL HIPERTÉRMICA (HIPEC) NO TRATAMENTO DAS METÁSTASES PERITONEAIS DO APÊNDICE CECAL - EXPERIÊNCIA INICIAL DO REAL INSTITUTO DE CIRURGIA ONCOLÓGICA (RICO)

, 2017
Thales Paulo Batista, Felipe Augusto Cruz Lopes Miranda, Mário Rino Martins, Rogério Luiz dos Santos, João Karimai, Euclides Dias Martins-Filho   +5 more
openalex   +1 more source

Metástases em sistema nervoso central de adenocarcinomas de pulmão que albergam mutações ativadoras do EGFR: resultados de sobrevida de uma abordagem multidisciplinar, incluindo EGFR-TKIs

, 2020
Guilherme Harada, Renata Rodrigues da Cunha Colombo Bonadio, Guilherme Nader Marta, Débora Z. Recchimuzzi, Gilberto de Castro   +4 more
openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

METÁSTASES HEPÁTICAS DE CÂNCER COLORETAL COMO FONTE DE REMETÁSTASES - A IMPORTANCIA PROGNÓSTICA DOS GRUPAMENTOS POUCO DIFERENCIADOS, BROTAMENTOS TUMORAIS E OUTROS FATORES ANATOMOPATOLÓGICOS

, 2017
Gilton Marques Fonseca, Evandro Sobroza de Mello, Sheila F. Faraj, Jaime Arthur Pirola Krüger, Fabrício Ferreira Coelho, Vagner Birk Jeismann, Ivan Cecconello, Paulo Herman   +7 more
openalex   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source