Results 21 to 30 of about 846,205 (205)
El linfoma primario de mama es una presentación rara del linfoma no Hodgkin. Se trata de una paciente de 20 años de edad con 36 semanas de gestación que presenta dolor lumbar y parestesia en miembros inferiores. Incidentalmente se detectan nódulos mamarios bilaterales BI-RADS (Breast Imaging Reporting and Data System) 4A.
Roberto J. González-Zambrana +3 more
openaire +2 more sources
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan +1 more
wiley +1 more source
ABSTRACT Pediatric radiation therapy presents unique challenges compared to adult treatments, including those of immobilization, potential need for sedation, and the critical importance of accurate, reproducible positioning. Additionally, heightened attention to imaging doses is necessary to minimize long‐term toxicity in survivors.
Parham Alaei +17 more
wiley +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source
Efectos divergentes de la inhibición de TGF-ß en metástasis óseas de cáncer de mama y pulmón
Fundamento: El objetivo de este estudio radica en la determinación de la validez del factor de crecimiento transformante β (TGF-β) como diana terapéutica en modelos de metástasis óseas derivadas de distintos tipos histopatológicos del cáncer de pulmón.
Luis-Ravelo D +7 more
doaj
ABSTRACT Background Pediatric bone sarcoma patients and survivors may experience psychosocial challenges related to childhood cancer after their intensive, body‐altering treatment. This cross‐sectional study aimed to evaluate generic and survivor‐specific psychosocial outcomes in a national cohort of pediatric bone sarcoma patients and survivors, and ...
Hinke van der Hoek +14 more
wiley +1 more source
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver +25 more
wiley +1 more source
El carcinoma de células de Merkel es un tumor cutáneo, infrecuente, altamente agresivo, con gran tendencia a la diseminación regional y a distancia, que generalmente ocurre en la cabeza y el cuello de las personas ancianas.
Paula Mejía Z. +2 more
doaj

