Results 41 to 50 of about 878,108 (245)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Cirugía del Uruguay, 1977 Aportamos una observación de hepatoma cuyo primer síntoma fue la presencia de un voluminoso tumor costal, siendo la biopsia la que demostró su carácter metastático.
Nicolás Davidenko +3 more
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Metástasis ovárica de carcinoma de células renales primario [PDF]
, 2008 Objetivo: Presentar un caso de metástasis ovárica secundaria a un carcinoma de células claras renal. Método/Resultados: Mujer de 52 años que consultó por metrorragias siendo inicialmente diagnosticada de carcinoma primario de ovario.
Álvarez Múgica,Miguel +7 more
core +1 more source
Frequency of metastasis to the submandibular gland among patients with oral squamous cell carcinomas
Revista Cubana de Estomatología, 2016 Introduction: the possibility of metastasis to the submandibular gland in patients with oral squamous cell carcinomas is a novel topic not frequently dealt with in scientific research.
Rafael Michel Coca +5 more
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Metástasis ganglionares de osteosarcomas [PDF]
, 1996 En este artículo presentamos dos pa cientes con osteosarcoma osteoblástico de tercio distal de fémur que cursaron con afectación ganglionar loco - regional.
Diaz, L. (L.) +5 more
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Revista Científica CMDLT, 2022 Introducción: El cáncer sincrónico ginecológico es una rara entidad con un especial interés clínico y patológico, se denomina así a aquellas neoplasias que se presentan en un mismo paciente, simultánea o sucesivamente.
Carmen María Aranguren Tuárez +2 more
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